Moderna: 30,000 Participants Enrolled in COVID-19 Vaccine Trial
The trial is investigating the efficacy, safety, and immunogenicity of mRNA-1273 at the 100mcg dose.
Geriatrics
Novel Pneumococcal Conjugate Vaccine Immunogenic in Phase 3 Trials
Results from PNEU-PATH demonstrated comparable immune responses following vaccination with Pneumovax 23 in both treatment groups for the 15 serotypes in V114.
Higher Levothyroxine Doses Linked to Afib in Older Patients
To evaluate the association, the study authors utilized healthcare databases from Ontario, Canada to identify adults 66 years of age and older with no history of AF who filled at least 1 prescription for levothyroxine.
Type of Anesthesia Not Linked to Dementia Risk in Older Adults
Dementia risk did not differ by general, regional anesthesia in seniors undergoing elective surgery.
Kynmobi Now Available to Treat Off Episodes in Parkinson Disease
Apomorphine is believed to treat off episodes associated with PD through stimulation of postsynaptic dopamine D2-type receptors within the caudate-putamen in the brain.
Metformin May Slow Cognitive Decline in Seniors With T2DM
Cognitive decline slower, dementia risk reduced in seniors with diabetes receiving metformin
Antidepressant, NSAID Identified as Culprits in SIADH Case
The patient noted that she was initiated on naproxen by her primary care physician 2 weeks prior to her presentation.
Ongentys Now Available as Add-On Treatment for Parkinson Disease
Ongentys is an oral, selective and reversible inhibitor of catechol-O-methyltransferase.
Aducanumab Gets Priority Review for Alzheimer Disease
The FDA has accepted for Priority Review the Biologics License Application for aducanumab (Biogen) for the treatment of Alzheimer disease.
Pimavanserin sNDA Under Review for Dementia-Related Psychosis
The FDA has accepted for filing the supplemental New Drug Application (sNDA) for pimavanserin (Nuplazid®; Acadia) for the treatment of hallucinations and delusions associated with dementia-related psychosis.
