Low-Dose Aspirin Does Not Prevent Depression in Older Adults
No significant difference seen in incidence rate of new CES-D-10 scores of ≥8 for aspirin, placebo
General Psychiatry
Benzodiazepine Use Linked to Risk for Ectopic Pregnancy
Excess of 80 ectopic pregnancies per 10,000 pregnancies found in women with benzodiazepine prescription.
Phase 3 Trial Evaluating Roluperidone in Schizophrenia Misses End Points
Minerva Neurosciences announced that its phase 3 trial of roluperidone (MIN-101) did not meet the primary and key secondary end points for the treatment of negative symptoms in schizophrenia.
Dayvigo Now Available for Insomnia Treatment
Dayvigo (lemborexant; Eisai) is now available for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance in adult patients.
Pharmacogenetics in Antidepressant Selection for Major Depressive Disorder
Presently, clinicians should be urged to view genetics as an additional tool in choosing prescriptions for MDD, as opposed to a replacement for complete clinical evaluation.
Unapproved Cannabidiol, Curcumin Injectables Marketed for Multiple Disorders Recalled
Biota Biosciences announced the voluntary recall of CBD Complex, Curcumin Complex, and Cannabidiol + Curcumin Injectables due to the products being marketed without the approval of the FDA.
Review Highlights Neuropsychiatric Presentations of COVID-19
Evidence presented for delirium during COVID-19, post-illness neuropsychiatric consequences for SARS, MERS
FDA to Review Manipulation-Resistant Stimulant Med for ADHD
AR19 is an investigational immediate-release, amphetamine formulated to prevent the manipulation of the pellets in the capsules for nonmedical use.
Dasotraline Development for ADHD, Binge Eating Disorder Halted, NDAs Withdrawn
n August 2018, the Food and Drug Administration (FDA) issued a Complete Response Letter (CRL) stating the application required additional data to further assess the efficacy and tolerability of dasotraline.
Differences in Anxiety, Depression According to Current and Former Smoking Status
Both stable current smokers and individuals who had quit exhibited significantly less anxiety but more depression.
