New Drug Product: Tolsura
This slideshow reviews drug information for Tolsura. This slideshow reviews drug information for Tolsura.
Fungal Infections
Treatment for Cryptococcosis Gets FDA’s Orphan Drug Designation
The Food and Drug Administration (FDA) has granted Orphan Drug designation to APX001 (Amplyx Pharmaceuticals) for the treatment of cryptococcosis.
New Treatment Option for Serious Fungal Infections Now Available
Tolsura, which contains the azole antifungal itraconazole, is formulated using the Company’s proprietary SUBA (SUper-BioAvailable) technology which improves the bioavailability of poorly soluble drugs.
FDA Approves Tolsura for the Treatment of Certain Systemic Fungal Infections
Tolsura is a new formulation of itraconazole, an azole antifungal, that utilizes the Company’s proprietary SUBA (SUper-BioAvailable) technology to improve the bioavailability of poorly soluble drugs.
Hypoglycemia Following Antifungal Tx in Patient With Type 1 Diabetes
“This is the first report of decreased insulin requirements in a patient with T1DM correlating with micafungin administration,” noted the authors.
Rezafungin Gets Fast Track, QIDP Status for Prevention of Invasive Fungal Infections
The Phase 3 ReSPECT prophylaxis trial of rezafungin in patients undergoing allogeneic bone marrow transplantation is anticipated to start in the first quarter of 2019.
NICU Antibiotic Use Rates Declined From 2013 to 2016
There was no correlation between the 2016 AUR and either proven infection or necrotizing enterocolitis. However, there was an association between the 2016 regional NICU AUR and surgical volume, mortality rate, and average length of stay
CDC: Greater Awareness of Valley Fever Needed Nationally
Seven in 10 patients had another condition diagnosed before coccidioidomycosis testing occurred, of whom the vast majority (83%) were prescribed antibacterial medications, 43% were hospitalized, and 29% had culture-positive coccidioidomycosis.
Prevalence of Antimicrobial-Contraindicated Drug Combo Prescribing Examined
Researchers performed a cross-sectional study that included multiple year pooled data (2003 to 2011) from the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS Outpatient Department).
Antifungal Use During Pregnancy and Risk of Stillbirth: What’s the Link?
Based on the findings, it was concluded that fluconazole use during pregnancy was not associated with significantly increased risks of stillbirth or neonatal death. However, the authors cautioned that the confidence intervals were wide and neither result was statistically significant.
