PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD
Among men with ischemic heart disease, coprescription of nitrates and PDE5 inhibitors not linked to increased risk for cardiovascular events
Among men with ischemic heart disease, coprescription of nitrates and PDE5 inhibitors not linked to increased risk for cardiovascular events
AvKARE says it is not aware of any patients being harmed by the recalled products
A recent Morbidity and Mortality Weekly Report (MMWR) highlights the risks associated with use of over-the-counter (OTC) products containing undeclared prescription ingredients as well as the importance of collaboration between various health departments and systems to ensure a prompt response to an outbreak.
The other tablet strengths — 5mg, 10mg, 20mg — will continue to be available in 30-count bottles.
Forty percent indicated that they were currently sexually active; sexual activity decreased with age. More than half (54%) of respondents agreed that sex is important to their overall quality of life, with men more likely to agree than women (70 versus 40%).
The manufacturers on the blister packs of these drugs show Acme Generics and Sun Pharma. The FDA also expressed concern that the seller may be distributing unapproved tadalafil, the generic version of Cialis
No significant effect for rosuvastatin, CandHCTZ, or both versus placebo in men aged 55 years
Sildenafil tablets are a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction.
These undeclared ingredients may interact with nitrates contained in some prescription medications (eg, nitroglycerin), and may decrease blood pressure to dangerous levels.
The association between melanoma among PDE5i users was only statistically significant for male patients with low PDE5i exposure and with low-stage melanoma.