Prenatal Exposure to Certain Antiseizure Meds Linked to Autism
Risks for ASD, intellectual disability may be increased with prenatal exposure to topiramate, valproate, certain duotherapies
Epilepsy
Inability to Afford Prescription Meds, Specialty Care More Likely for Adults With Epilepsy
Those with active or inactive epilepsy are also more likely to have Medicaid and other public insurance
Posttraumatic Epilepsy More Likely to Be Drug Resistant
Lowest quality of life reported for those with posttraumatic epilepsy, drug-resistant epilepsy
Concentrations of Certain Antiseizure Meds Drop During Pregnancy
Dose-normalized concentrations of lamotrigine, levetiracetam, lacosamide, oxcarbazepine, and zonisamide decreased during pregnancy
Oxcarbazepine Tied to Nontrauma Fracture in Children Aged 4 to 13 With Epilepsy
Initiating oxcarbazepine, but not levetiracetam, linked to increased incidence rate ratio for nontrauma fracture
Cognitive Outcomes Studied for In Utero Exposure to Antiseizure Meds
No significant differences in language development seen at age 2 years for children born to mothers with epilepsy
Neonates With Acute Seizures May Be Overmedicated
Those discontinuing seizure meds after symptom resolution in the hospital have same neurodevelopment, epilepsy outcomes at 24 months
Room Temperature Stable Fosphenytoin Gets FDA Approval
The product is a ready-to-dilute, room temperature stable formulation of fosphenytoin for IV injection, which allows for point-of-care storage.
FDA Requires Boxed Warning Update for Benzodiazepines
Benzodiazepines are widely used to treat a variety of conditions including anxiety disorders, insomnia and seizures.
Epidiolex Approved for Tuberous Sclerosis Complex-Associated Seizures
Epidiolex is a pharmaceutical formulation of highly purified cannabidiol.
