Dyslipidemia

LDL-C Lowering Combo Therapy Nexlizet Now Available

Nexlizet (bempedoic acid and ezetimibe; Esperion) is now available for use as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C.

Two PCSK9 Inhibitors for LDL Cholesterol Promising in Studies

Evolocumab and alirocumab, monoclonal antibodies that inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9), reduce low-density lipoprotein (LDL) cholesterol levels in the longer term, according to two studies published in the New England Journal of Medicine.