Imsidolimab Gets Orphan Drug Designation for Generalized Pustular Psoriasis
Generalized pustular psoriasis is a rare systemic inflammatory disease characterized by inflamed skin and small pustules.
Dermatological Disorders
Clinical Challenge: Scaly Bumps on Feet and Ankles
A 57-year-old woman is referred for evaluation of scaly bumps on her feet and ankles. She states that the condition has been present for approximately 20 years. Aside from mild itch, she had no symptoms of significance associated with the lesions. The patient’s medical history is significant for hypertension but not thyroid disease. Examination reveals…
Investigational Oral JAK Inhibitor Gets Breakthrough Tx Status for Alopecia Areata
The FDA has granted Breakthrough Therapy designation to CTP-543 (Concert Pharmaceuticals), an oral Janus kinase (JAK) inhibitor for alopecia areata.
Mylan Recalls One Lot of Daptomycin for Injection
According to Mylan, the administration of the recalled product may lead to “serious adverse events including, but not limited to, local irritation, vasculitis/phlebitis, antigenic or allergic reactions, and microvascular obstruction, including pulmonary embolism.”
FDA Approves Qwo to Treat Moderate to Severe Cellulite
Results from both studies showed treatment with Qwo was associated with greater reductions in cellulite severity compared with placebo as measured by CR-PCSS and PR-PCSS scales at day 71.
Clinical Challenge: Scarred Hypertrophic Plaque on Leg
A 26-year-old woman is referred for evaluation of a bump under the skin of her left hand. The lesion has been slowly increasing in size over the course of a year. The patient denies previous trauma to the area and states the lesion is asymptomatic. Her medical history is unremarkable. Physical examination reveals a solitary, firm, flesh-colored papule. Light palpation does not elicit tenderness. No similar lesions are noted elsewhere.
Sivextro Approval Expanded to Include Pediatric Patients
The FDA has expanded the approval of Sivextro.
Keytruda Approved for Cutaneous Squamous Cell Carcinoma
The FDA has approved Keytruda (pembrolizumab; Merck) for the treatment of patients with recurrent or metastatic cutaneous squamous cell carcinoma (cSCC) that is not curable by surgery or radiation.
Clinical Challenge: Asymptomatic Lesion on the Foot
A 4-year-old girl is referred for evaluation of a lesion on her foot that her parents noticed approximately 6 weeks ago. The patient is not bothered by the lesion and does not have similar marks elsewhere on her body. She is of normal weight, height, and mentation for her age. Triamcinolone cream was initially prescribed…
Arazlo Lotion Now Available for Acne Vulgaris
Arazlo™ (tazarotene; Bausch Health Companies) Lotion 0.045% is now available for the topical treatment of acne vulgaris in patients aged ≥9 years.
