No Pfizer COVID-19 Vaccine Expected Before Election
Company has reversed its previous claims that it would apply for the approval in October.
COVID19
NIH: Immune Modulators to Be Investigated for COVID-19
The NIH-led trial will assess 3 drugs: infliximab, a tumor necrosis factor blocker, abatacept, a selective T cell costimulation modulator, and cenicriviroc, an investigational immunomodulator that blocks 2 chemokine receptors, CCR2 and CCR5.
Reinfection With SARS-CoV-2 Described in 25-Year-Old
Patient had two positive tests in April and June 2020, separated by two negative tests in May 2020.
MPR Weekly Dose Podcast Episode 54
This week: News of another vaccine trial being put on hold; A trial assessing hyperimmue globulin beings; An NDA for IV tramadol is rejected; FDA Committees vote on novel schizophrenia and bipolar I disorder therapy; And a first approval for Ebola.
COVID-19 Antibody Treatment Study Paused
ACTIV-3 study, testing use of an antibody therapy with remdesivir, paused ‘out of an abundance of caution’.
NIH: Study Will Identify Most Promising Therapies for COVID-19
So far, the therapies scheduled to be part of the trial are risankizumab, an interleukin-23 antagonist, and lenzilumab, an anti-human granulocyte macrophage-colony stimulating factor monoclonal antibody.
Individuals With Blood Group O Have Lower Risk for COVID-19
And more COVID-19 patients with blood group A or AB require mechanical ventilation, CRRT.
Second COVID-19 Vaccine Trial Paused for Unexplained Illness
Johnson & Johnson stopped its COVID-19 vaccine trial, which began phase 3 testing last month.
Remdesivir Cuts Time to COVID-19 Recovery
However, no significant difference in mortality found between remdesivir and placebo groups.
Trial Evaluating Anti-SARS-CoV-2 Hyperimmune Globulin Begins
The antibody solution is derived from plasma donated by healthy individuals who have recovered from COVID-19.
