FDA Rejects Gefapixant NDA for Chronic Cough
The application includes data from the two phase 3 studies, which evaluated the efficacy and safety of gefapixant in adults with refractory or unexplained chronic cough for at least 1 year.
Cough and Cold
Results Mixed for Use of Zinc for Acute Viral RTIs in Adults
Some evidence suggests zinc might shorten duration of symptoms, but further research needed to address many unanswered questions
Child Fatalities Linked to OTC Cold and Cough Meds Described
Sixty percent of fatalities occurred in children younger than 2 years of age and 55 percent involved nontherapeutic intent by a caregiver
Corticosteroid Responsiveness Assessed in Patients with Chronic Cough
The most common presenting complaints included shortness of breath, rhinorrhea, and hoarseness.
FDA: Abuse/Misuse of OTC Nasal Decongestant Can Lead to Major Health Complications
Since January 1, 2000, there have been 460 documented cases of propylhexedrine abuse or misuse reported to US poison control centers.
Gefapixant Under Review for Refractory Chronic Cough
The NDA submission is based on data from the double-blind, placebo-controlled phase 3 studies, COUGH-1 and COUGH-2.
Mucinex Children’s FreeFrom OTC Cough/Cold Products Now Available
Mucinex® Children’s FreeFrom™, a new line of over-the-counter cough and cold products free from artificial flavors, colors, and dyes, has been made available by Reckitt Benckiser.
OTC Medicines Containing “Clean” Inactive Ingredients Launched
Genexa has launched 4 over-the-counter (OTC) medicines that contain no artificial ingredients.
Statistically Significant Reduction in Cough Frequency Observed in Gefapixant Trials
The double-blind, placebo-controlled studies, COUGH-1 and COUGH-2, included 730 and 1314 adult patients with refractory or unexplained chronic cough for at least 1 year, respectively.
Betadine OTC Product Line Expands With Antiseptic Sore Throat Gargle
Betadine Antiseptic Sore Throat Gargle is indicated for adults and children 12 years of age and older.
