CNS Cancers

Risks of Whole Brain Radiation Tx May Outweigh Benefits

Targeted radiation in the treatment of brain metastases leads to less cognitive damage than radiation for the entire brain, while survival is similar, researchers reported at the annual meeting of the American Society of Clinical Oncology. In a second study, researchers report that early trials of a new form of gene therapy may give hope to patients battling glioblastoma.

First Tx for Pediatric High-Risk Neuroblastoma Approved

The Food and Drug Administration (FDA) has approved Unituxin (dinutuximab; United Therapeutics), the first therapy to be approved for pediatric patients with high-risk neuroblastoma for use as part of a multimodal regimen including surgery, chemotherapy and radiation therapy for patients who achieved at least a partial response to prior first-line multiagent, multimodality therapy.

Avastin Gains New Ovarian Cancer Indication

Genentech announced that the Food and Drug Administration (FDA) has approved Avastin (bevacizumab) in combination with chemotherapy for the treatment of women with platinum-resistant, recurrent ovarian cancer.