Cirrhosis

Higher levels of alcohol and tobacco use put men at risk for liver disease, such as cirrhosis and alcoholic liver disease. Men who have sex with men are at increased risk for viral hepatitis B, and should be screened accordingly.

Trial Investigating Treatment for Hyperammonemia in Cirrhosis Discontinued

Synologic, Inc announced that following disappointing top-line data from a phase 1b/2a study, the Company will discontinue the development of SYNB1020 for the treatment of hyperammonemia. The randomized, double-blinded, placebo-controlled phase 1b/2a study consisted of two parts designed to evaluate the safety, tolerability, and pharmacodynamics of SYNB1020 in hepatic insufficiency and cirrhosis patients.  Results showed…