Chronic Adverse Effects From Anti-PD-1 Immunotherapies Common
About 43 percent of patients who receive anti-PD1 therapy for advanced melanoma have chronic immune-related adverse effects
Cardiovascular Disease
Rare Thrombosis, Thrombocytopenia Seen After AstraZeneca COVID-19 Vaccine
Reports document 16 reactions in young European patients following first dose of ChAdOx1 nCoV-19 vaccine
Mortality Lower With PDE5i Treatment in Men With Stable CAD
Mortality risk lower with PDE5i treatment versus alprostadil treatment; similar links seen for MI, heart failure, CV mortality risks
Do Successive Transfers of an Emergency Patient Amount to an EMTALA Violation?
This month we look at a case involving the Emergency Medical Treatment and Labor Act, commonly referred to as EMTALA. EMTALA was enacted by Congress in 1986 as part of the Consolidated Omnibus Budget Reconciliation Act (COBRA) of 1985. The act was designed to prevent hospitals from ‘patient dumping’; transferring uninsured or Medicaid patients to…
Trial Evaluating Dapagliflozin in Hospitalized COVID-19 Patients Misses Endpoints
The DARE-19 trial evaluated dapagliflozin in addition to standard of care in reducing disease progression, clinical complications and all-cause mortality in 1250 adults hospitalized with COVID-19.
Medtronic Stent Graft System Recalled Due to Fractures, Endoleaks
The recall was initiated due to reports of stent fractures and endoleaks.
MPR Weekly Dose Podcast 74
Back to regular programming this week with a summary of the top news, which includes updated travel guidance; Six month efficacy data for the Moderna and Pfizer-BioNTech vaccines; Vial doses increased for Moderna; A new ADHD drug is approved; And the FDA has issued a safety communication regarding lamotrigine.
Stethoscope Remains Best Way to Monitor Fetal Distress During Labor
Review of 33 studies, including seven monitoring methods, shows no benefit from newer strategies
Medicare Claims Database Useful for Detecting Arrhythmogenic Risk of QT-Prolonging Drugs
Study authors evaluated whether using an observational study that includes Medicare claims data could detect the proarrhythmic risk of medications known to prolong the QT interval.
Decline in Mean BP Among US Children, Teens Between 1999 to 2018
However, authors warn that stagnation and possible increase in more recent years may indicate reversal of trend
