Bone Disorders

Does Osteoporosis Treatment Reduce Overall Mortality in Addition to Fracture Risk?

According to a recent meta-analysis, no significant association was observed between pharmacotherapies used for osteoporosis treatment and mortality rate, despite previous studies suggesting the treatments, particularly bisphosphonates, lower overall mortality. To investigate this association, study authors searched various databases and conference abstracts for randomized placebo-controlled studies in which drug therapies were evaluated for a year…

FDA Panel Votes on Nintedanib for Systemic Sclerosis Associated Interstitial Lung Disease

The Food and Drug Administration’s (FDA) Arthritis Advisory Committee voted 10 to 7 in favor of approval of Ofev (nintedanib; Boehringer Ingelheim) for the treatment of systemic sclerosis associated with interstitial lung disease (ILD). The recommendation was based on data from the phase 3 SENSCIS trial which evaluated the efficacy and safety of nintedanib in…