Erythropoietin May Up Risk for Hip Fracture in Hemodialysis Patients
Risk for hip fracture increased with EPO doses of 50 to 149, 150 to 299, and 300 or greater vs <50 units/kg/week
Bone Disorders
FDA Approves 3D Printed Implant for Avascular Necrosis of the Talus
The approval is supported by data from 31 patients and 32 talus replacement surgeries.
Topical Corticosteroid Use and Osteoporosis Risk Examined
To determine the association between cumulative exposure of potent and very potent TCSs and osteoporosis and MOF risk, study authors utilized the Danish nationwide registries.
Continuing Treatment Not Beneficial After 5 Years of Bisphosphonates
No difference seen in cumulative incidence of hip fracture for continuing therapy for two, five additional years versus discontinuing
Most Users Report Cannabidiol Use for Treatment of Diagnosable Conditions
Psychiatric, orthopedic, and sleep issues most commonly cited in a Reddit forum
Vosoritide NDA for Achondroplasia Submitted for Review
Vosoritide is an investigational analogue of C-type natriuretic peptide.
Longer Bisphosphonate Drug Holiday May Up Fracture Risk
For those with previous vertebral fracture, major osteoporotic fractures increased with holidays >12 months.
Canakinumab Explored as Therapy for Large-Joint Osteoarthritis
Exploratory analysis reveals total hip/knee replacement rate reduced with canakinumab vs placebo.
Vertebral Fractures Up With Long-Term Delay of Denosumab
Increase in risk with long delay of subsequent doses not significant for composite of all fracture types
Contraceptives Beneficial for Premature Ovarian Insufficiency
Combined oral contraceptives linked to improvement in bone mass, similar to that with high-dose HT.
