May 2022: Drug Pipeline Updates
Stay up-to-date on the latest drugs in development.
Asthma
Albuterol/Budesonide Fixed-Dose Combo Rescue Inhaler to Get FDA Review
The NDA submission is supported by data from the phase 3 MANDALA trial, which included 3132 patients with moderate to severe asthma.
Which Biologics Reduce Allergic Response, Airway Hyperresponsiveness in Asthma?
What biologic therapies effectively treat airway hyperresponsiveness in asthma, and what do these therapies show about the underlying biology of asthma?
TRAVERSE Trial of Dupilumab for Severe Oral Corticosteroid-Dependent Asthma
TRAVERSE trial findings on the efficacy, safety, and OCS-sparring effect of dupilumab for severe OCS-dependent asthma were presented at ATS 2022.
How Does Omalizumab Affect Antitussive Use in Patients With Allergic Asthma?
Does omalizumab therapy for patients with moderate to severe allergic asthma affect these patients’ use of antitussives?
Switching Inhalers in Patients With Asthma and COPD
Should patients with asthma or COPD have their inhaler regimens switched for nonclinical reasons? A systematic review examined real world evidence on this subject.
Does Depression Influence Asthma Exacerbation Frequency?
To what extent does depression influence asthma exacerbations? A population-based study presented at ATS 2022 examined the link between exacerbations and depression.
The Gut Microbiome and ICS Response to Wheezing in Pediatric Asthma
Among children with asthma, are inhaled corticosteroids effective in controlling wheezing that is associated with these children’s gut microbiome?
Treating Severe Eosinophilic Asthma: Mepolizumab vs Benralizumab
What is the difference in efficacy between mepolizumab and benralizumab, 2 biologics approved for the treatment of severe eosinophilic asthma?
Azithromycin and Recurrent Wheeze in Children After Severe RSV Bronchiolitis
Research presented at AAAAI assessed the effectiveness of oral azithromycin in reducing recurrent wheeze in young children.
