Volatile Anesthetics Do Not Reduce Deaths in Elective CABG
No significant difference seen for patients undergoing CABG with volatile anesthesia, total IV anesthesia
Anesthetics
Brief Anesthesia in Infancy Does Not Mar Neurodevelopment
Neurodevelopmental outcomes at 5 years of age are equivalent after brief general anesthesia or awake-regional anesthesia in infancy.
Glass Particulate Identified in Certain Vials of Vecuronium Bromide
Vecuronium Bromide, a neuromuscular blocker, is indicated as adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Pediatric Anesthesia Does Not Affect Development Outcomes
Researchers examined the correlation between surgical procedures that require general anesthesia before primary school entry and child development in a retrospective sibling-matched cohort study, including sibling pairs aged 5 to 6 years with the same birth mother.
Drug Used for Reversal of Neuromuscular Block Recalled Due to Mislabeling
Neostigmine Methylsulfate Injection, a cholinesterase inhibitor, is indicated to reverse the effects of non-depolarizing neuromuscular blockers after surgery.
AMA: Docs Declare Drug Shortages Public Health Emergency
The AMA will urge the Department of Health and Human Services and Department of Homeland Security to examine drug shortages as a national security initiative in response to hazards that pose a threat to the resilience of drug production.
Post-Op Pain Treatment Gets Breakthrough Therapy Designation
The Company indicated that they will work towards an New Drug Application submission for the treatment in the second half of 2018.
Children Can Drink Clear Fluids Until 1 Hour Before Anesthesia
Increased thirst and irritability are reported with prolonged fasting period, as well as detrimental physiological and metabolic effects. No increased risk of pulmonary aspiration was reported with a 1-hour clear fluid policy and studies demonstrated that the stomach was empty.
Dexmedetomidine Cuts γ-Aminobutyric Acid Receptor Function
The researchers found that dexmedetomidine reduced the etomidate-induced sustained increase in α5 γ-aminobutyric acid type A receptor cell-surface expression (etomidate: 146.4 ± 51.6%; etomidate + dexmedetomidine: 118.4 ± 39.1% of control).
