A recently published report describes the case of a 49-year-old female patient who experienced aplastic anemia secondary to long-term metronidazole use and highlights the importance of monitoring for metronidazole-induced hematologic dyscrasias.
This is currently the only liquid formulation of this agent available in the US.
For individuals without cardiovascular disease, use of aspirin is associated with a reduced risk for cardiovascular events and an increased risk for major bleeding, according to a newly published meta-analysis.
The global Phase 3 program consists of more than 9,000 patients.
The safety and efficacy of Ultomiris in patients with PNH was assessed in 2 open-label, randomized, active-controlled, non-inferiority Phase 3 studies.
App uses color and metadata from fingernails to detect hemoglobin levels in the blood
The approval was based on data from a single-arm, open-label sequential cohort study in which patients received Promacta in combination with horse antithymocyte globulin (h-ATG) and cyclosporine.
Retacrit will be priced 57.1% below the Wholesale Acquisition Cost (WAC) of Procrit and 33.5% below the WAC of Epogen, at $11.03 per 1000 Units/mL.
If blood with poorly matched antibodies is transfused, the procedure is more likely to lead to red blood cell destruction and a transfusion reaction, the agency explained.
The Company is currently planning a Phase 2 trial of PTG-300 in beta-thalassemia patients which they expect to begin before the end of the year.
