Gene Therapy Fast Tracked for APOE4 Associated Alzheimer Disease
The investigational adeno-associated virus mediated gene therapy is being developed to deliver the protective APOE2 gene to the CNS.
Alzheimer Disease
Dexmedetomidine Oral Film Gets Breakthrough Tx Status for Acute Agitation With Dementia
BXCL501 is an oral thin film formulation of dexmedetomidine, a selective alpha-2a receptor agonist.
FDA Extends Review of Aducanumab for Alzheimer Disease
Aducanumab, a human monoclonal antibody, binds to aggregated β-amyloid and promotes removal of amyloid from the brain.
Experimental Drug for Alzheimer Disease Shows Promise
After six to 12 months of treatment with the drug, patients no longer had amyloid protein plaques.
FDA Panel Votes on Aducanumab for Alzheimer Disease
The investigational treatment, which is administered as a monthly intravenous infusion, binds to aggregated β-amyloid and promotes removal of amyloid from the brain.
CNS-Active Meds Often Prescribed for Older Adults With Dementia
Overall, Rx filled for antidepressants in 49.8 percent, opioids in 29.8 percent, anxiolytics in 26.8 percent
MPR Weekly Dose Podcast Episode 47
This week we have remdesivir news; A new opioid and spinal muscular atrophy treatments are approved; A sublingual epinephrine treatment; And the latest on Biogen’s investigational Alzheimer disease treatment. Also, we have a brief summary of the other drugs in the pipeline from the past week.
Aducanumab Gets Priority Review for Alzheimer Disease
The FDA has accepted for Priority Review the Biologics License Application for aducanumab (Biogen) for the treatment of Alzheimer disease.
Vaccination Linked to Reduced Alzheimer Disease Risk
At AAIC 2020, 2 presentations separately discussed observing a reduced risk of AD in patients who received the influenza and pneumonia vaccines.
Aducanumab BLA for Alzheimer Disease Submitted for FDA Review
Biogen has submitted its Biologics License Application (BLA) to the Food and Drug Administration (FDA) for aducanumab as a treatment of Alzheimer disease (AD).
