Removal of EHR Warning Linked to Increase in Cephalosporin Use in Patients With Penicillin Allergy
After removal of the warning, cephalosporin use increased from 17.9% to 27.0% at the intervention site.
Allergies
MPR Weekly Dose Podcast 76
In this week’s pod, the FDA review the Emergency Use Authorization for bamlanivimab; Issues are identified at a Janssen manufacturing facility; Merck halts trials for investigational COVID therapy; A novel contraceptive is approved; And Ragwitek has its approval expanded.
Rash Following Medication Change Prompts Evaluation of Excipient Allergy
The patient developed a generalized maculopapular rash approximately 3 hours after receiving warfarin.
Ragwitek Approved for Pediatric Patients With Ragweed Pollen Allergy
The approval was based on data from a phase 3 trial that assessed Ragwitek in 1022 patients 5 to 17 years of age with a history of ragweed-induced rhinoconjunctivitis and sensitivity to short ragweed.
Self-Administration Option Approved for Xolair Prefilled Syringe
Xolair, an anti-immunoglobulin E antibody, is indicated for the treatment of moderate to severe persistent asthma, chronic idiopathic urticaria, and nasal polyps.
Frequency Low for Dual Allergy to Cefazolin, Natural Penicillins
Evidence suggests that most patients with penicillin allergy history could safely receive cefazolin for surgical prophylaxis
FDA Expands Use of Bioelectronic Device ClearUp to Include Sinus Congestion
The bioelectronic device was previously approved for treating sinus pain due to allergic rhinitis.
More Frequent Disinfectant Use Tied to Uncontrolled Asthma
Findings seen in a survey of U.S. adults with asthma during the COVID-19 pandemic
Mepolizumab Improves Symptoms in Chronic Rhinosinusitis With Nasal Polyps
Mepolizumab reduces disease symptoms in patients with chronic rhinosinusitis with nasal polyps, according to the results of a randomized, double-blind, multicenter study.
Exhalation Delivery System With Fluticasone Improves Sleep in Nasal Polyposis
In patients with moderate to severe chronic rhinosinusitis with nasal polyposis, treatment with an Exhalation Delivery System With Fluticasone (EDS-FLU) is associated with improved sleep scores.
