Off-Label Baclofen Use for Alcohol Use Disorders: Is it Effective?
Data showed a significant effect on abstinence rates with the use of baclofen (odds ratio [OR] 2.67, 95% CI: 1.03, 6.93) but no other significant effects on treatment efficacy (heavy drinking days SMD -0.26, 95% CI: -0.68, 0.15) or mechanism of action (craving SMD: -0.13, 95% CI: -0.36, 0.09) were seen.
