Anti-CLL1 CAR T Cells Produce Responses in Pediatric Acute Myeloid Leukemia
Eight patients had a complete response within 1 month of infusion.
Acute Myeloid Leukemia
Patients With Acute Myeloid Leukemia May Have Suboptimal Outcomes Because of Fears of Treatment Side Effects
Researchers sought to determine whether patients with AML were being undertreated due to patient fear about side effects to treatment.
Aspacytarabine Is Safe, Effective in First-Line Acute Myeloid Leukemia
Researchers sought to determine whether first-line aspacytarabine would be safe and effective in patients with AML who cannot tolerate chemotherapy.
Poor COVID-19 Outcomes Among Patients With Hematologic Malignancies: Results From ECOVIDEHE
Patients with AML or MDS were significantly more likely to die from COVID-19 vs other HMs. Most treatments did not improve survival outcomes — except corticosteroids.
Gilteritinib-Azacitidine Tested in R/R FLT3-Mutated AML
Now that the phase 2 dose is established, a randomization cohort will test the efficacy of the treatments in the LACEWING trial.
Disadvantaged Neighborhood Status Increased Risk for Death From AML
Census tract affluence, disadvantage, and segregation were all significant predictors of leukemia-related death.
Study Found Gilteritinib Superior to Salvage Chemotherapy in FLT3-mutated Refractory AML
The researchers examined 37 recurrently mutated genes in AML using next-generation sequencing.
