EDS_FLU produced higher systemic exposure than Flonase and substantially lower systemic exposure than Flovent 440mcg, indicating that drug deposition is greatly improved with EDS vs. conventional nasal spray.
Based on the pathophysiological and clinical characteristics of N-ERD, anti-IL 5 therapy may be effective in this patient subgroup.
Patients with hereditary angioedema (HAE) on long-term prophylaxis with attenuated androgen (LTP-AA) appeared to have a higher risk for cardiovascular disease but a lower number of neoplasms.
The XTEND-CIU study assessed patients aged ≥12 years for the safety and efficacy of longer-term omalizumab treatment (48 weeks) and helped to better understand drug discontinuation in patients with chronic idiopathic urticaria.
Patients in the study were ≥13 years old, had a <50% of normal functional C1INH level, and a history of at least 4 monthly HAE attacks for at least 3 months.
Association strongest for the vitamin E isoform -tocopherol, found in safflower, sunflower oils
Analysis indicated that skin attacks were treated more frequently in early self-treaters compared to late treaters.
The study evaluated subcutaneous dupilumab 300mg given weekly up to 3 years in adults with atopic dermatitis.
Two long-term studies evaluated satisfaction among PIDD patients.
Food intake was categorized as low, medium, or high based on the amount consumed during the study period.
