Your search for severe asthma returned 696 results

The BLA submission included data from the pivotal phase 3 NAVIGATOR trial that assessed tezepelumab in 1061 patients with severe, uncontrolled asthma.

Eating fast food ≥3 times per week is associated with an increased risk of severe asthma, rhinoconjunctivitis, and eczema among children and adolescents, while eating fruit seems to be protective against severe asthma.

Incidence of events indicating loss of asthma control lower with itepekimab monotherapy in phase 2, proof-of-concept trial

The study was designed to examine the prescribing patterns at a large academic teaching center to identify patients who have taken more than one biologic asthma medication, either sequentially or simultaneously, and to analyze the outcomes.

Peak expiratory flow increases were greater with benralizumab than placebo in patients with severe eosinophilic asthma.

Findings from a phase 3b trial showed that a majority of patients with severe eosinophilic asthma treated with benralizumab (Fasenra; AstraZeneca), an interleukin-5 antagonist, were able to eliminate or reduce oral corticosteroid (OCS) use. The open-label, single-arm PONENTE trial assessed the efficacy and safety of reducing OCS use after initiating treatment with benralizumab in nearly…

Trial enrolled children from disadvantaged urban neighborhoods who have exacerbation-prone eosinophilic asthma

Tezspire is a first-in-class human monoclonal antibody that works by blocking thymic stromal lymphopoietin, an epithelial cytokine involved in the initiation and persistence of airway inflammation.

Nair, P, MD, PhD. Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma. DOI: 10.1056/NEJMoa1703501.

Patients with asthma are at higher risk of pulmonary embolism, particularly if the asthma is severe or they take oral corticosteroids.