Your search for proton pump inhibitor returned 249 results

Is the use of proton pump inhibitors associated with empyema and lung abscess? Presenters at CHEST 2022 analyzed a large data base to address this question.

Is the use of proton pump inhibitors associated with empyema and lung abscess? Presenters at CHEST 2022 analyzed a large data base to address this question.

Findings showed that children who were initiated on PPIs were 57% more likely to be diagnosed with asthma.

Type 2 diabetes risk increased with increasing length of PPI use, particularly use for more than two years.

Small but significant risk seen for upper-limb and lower-limb fractures

The researchers found that a larger proportion of cases than controls had prior PPI use (70 vs 63%) or histamine-2 receptor antagonist use (25 vs 23%).

The case involved a 32-year-old male who was prescribed pantoprazole after initially presenting with dyspepsia-like symptoms.

The authors found that compared to the use of H2RA therapy, patients initiated on PPI therapy had a 25% increased risk of death (hazard ratio [HR] 1.25, 95% CI: 1.23-1.28).

The extent of risk also depended on the specific PPI taken.

Patients who are taking proton pump inhibitors (PPIs) may be at increased risk for kidney function decline, chronic kidney disease (CKD), and kidney failure.