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Objective: The aim of this study was to determine the extent of drug interactions affecting levothyroxine, using study drugs often co-administered to patients on long-term levothyroxine therapy. Design: A retrospective population analysis linking biochemistry and prescription data between 1 January 1993 and 31 December 2012 was used.

Thyroid 15mg (¼ grain), 30mg (½ grain), 60mg (1 grain), 90mg (1 + ½ grain), 120mg (2 grains), 180mg (3 grains)+, 240mg (4 grains), 300mg (5 grains)+; tabs; +scored. Each grain of thyroid contains liothyronine (T3) 9mcg and levothyroxine (T4) 38mcg.

Pharmacological treatments for thyroid disorders, including hypothyroidism, hyperthyroidism, and thyroid eye disease.

Levothyroxine sodium 13mcg/mL, 25mcg/mL, 37.5mcg/mL, 44mcg/mL, 50mcg/mL, 62.5mcg/mL, 75mcg/mL, 88mcg/mL, 100mcg/mL, 112mcg/mL, 125mcg/mL, 137mcg/mL, 150mcg/mL, 175mcg/mL, 200mcg/mL; oral soln; contains glycerol.