Tolsura is a new formulation of itraconazole, an azole antifungal, that utilizes the Company’s proprietary SUBA (SUper-BioAvailable) technology to improve the bioavailability of poorly soluble drugs.
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The summary below gives an overview of important additions and changes MPR has made to its drug database through the end of December. The chart below provides highlights of key monograph updates made this month (not an inclusive list). Click on the name of the drugs to view the full monographs on eMPR.com. Key: D=Dosing,…
There were 252 patients with EKG results included for the analysis; they were given concomitant therapy for median 7 days.
Compared with itraconazole, amphotericin treatment correlated with significantly faster clinical resolution and fungal clearance and with significantly lower rates of relapse and immune reconstitution inflammatory syndrome.
Results showed that 5 of the 6 bulb packages tested positive for triazole-resistant A. fumigatus.
List of different formulations (eg, tablets, capsules, liquids, topicals, injections, etc) available for the various prescription and over-the-counter antifungal therapies.
The Food and Drug Administration (FDA) has approved an update to the labeling for Noxafil (posaconazole; Merck) regarding an interaction with vincristine.
The Food & Drug Administration has granted Orphan Drug designation to PUR1900 (Pulmatrix) for the treatment of pulmonary fungal infections in patients with cystic fibrosis (CF).
Not only are prescription agents known to affect heart failure (HF), various over-the-counter and complementary medications have also been associated with causing or worsening HF as well.
The most severe cases involved doses ranging from 70mg-1600mg daily, which is 4-100 times the recommended dose.