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The FDA has notified healthcare professionals and patients that prescription proton pump inhibitors may cause hypomagnesemia if taken for prolonged periods of time (in most cases, longer than one year).
Case Studies
While structurally similar to amiodarone, the antiarrythmic agent dronedarone does not carry the same risk of severe organ toxicity. However, the potential proarrhythmic effects of dronedarone appear to be an issue of concern, particularly in a new case study highlighted in the journal Pharmacotherapy.
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Actavis has issued a nationwide recall of Digitek (digoxin tablets) due to the possibility that tablets with double-thickness, containing twice the approved level of active ingredient, may have been commercially released.
News
The patient was discharged from the hospital with a drug regimen which included aspirin, carvedilol, digoxin, valsartan, and furosemide.
News
The findings point to "minimal to no measurable effect" in lowering the concomitant use.
Drug Monograph Updates
The summary below gives an overview of some of the important additions and changes MPR has made to its drug database through the end of October. The chart below provides highlights of the 118 key monograph updates made this month (not an inclusive list).
News
Covis announced the launch of two new dosage strengths for Lanoxin (digoxin): 0.0625mg and 0.1875mg strength tablets.
News
Many of the interactions are minor, but there are some drug combinations that should be avoided.
Drug Monograph Updates
The summary below gives an overview of some of the important additions and changes MPR has made to its drug database through the end of November. The chart below provides highlights of the 118 key monograph updates made this month (not an inclusive list).
News
The Canadian Cardiovascular Society has updated guidelines relating to the management of atrial fibrillation (AF); the guidelines were published online in the Canadian Journal of Cardiology.