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Drug Monograph

Digoxin Oral Solution

Digoxin 0.05mg; per mL; lime-flavored; contains alcohol 10%.

Study Examines Hazard of Mortality for A-Fib Patients Receiving Digoxin

However, compared with patients not on digoxin, patients with a serum digoxin concentration ≥1.2 ng/mL had a 56% increased hazard of mortality (adjusted HR, 1.56; 95% confidence interval, 1.2 to 2.04). For each 0.5-ng/mL increase (P=0.001), there was a 19% higher adjusted hazard for death, and these results were similar in patients with and without heart failure.
Drug News

New Review Casts Doubt on Digoxin for Afib

A recent review on the role of digoxin in atrial fibrillation (AF) has concluded that clinicians should avoid using digoxin monotherapy for rate control in patients with AF when other options are available.

Digoxin Dosing

A calculator for determining Digoxin Dosing.

Digoxin Ups Risk of Death in A-Fib, CHF Patients in Largest Study to Date

Previous research has yielded conflicting evidence on the use of digoxin in patient with atrial fibrillation (AF) or congestive heart failure (CHF), but the largest systematic review and meta-analysis suggests that there is an increased risk of all-cause mortality with digoxin use in these patients.
Drug News

Digoxin-Dronedarone Interaction Investigated

The use of digoxin in atrial fibrillation has remained controversial because of its narrow therapeutic window and its possible contribution to ventricular tachyarrhythmias and severe bradyarrhythmias.