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Bleeding disorders
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Generic Name and Formulations:

Thrombin [recombinant] 5000 IU, 20000 IU; per vial; pwd for topical use after reconstitution; preservative-free.

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Indications for RECOTHROM:

Aid to hemostasis for minor bleeding/oozing from capillaries and venules when standard surgical techniques are inadequate or ineffective. May use with absorbable gelatin sponge.


Apply directly to bleeding area, or soak into absorbable gelatin sponge and apply in a single layer.


Not recommended.


Not for direct injection into circulatory system. Not for treatment of massive or brisk arterial bleeding. Hypersensitivity to hamster proteins.


Avoid systemic absorption (thrombosis may occur). Hypersensitivity to snake proteins. Pregnancy (Cat.C).

Pharmacological Class:

Topical hemostatic.

Adverse Reactions:

Incision site complication, infection, pain, bleeding, nausea/vomiting, cardiac events, thromboembolic events.

How Supplied:

Single-use vial (5000 IU, 20000 IU)—1 (w. diluent, supplies)
20000 IU Recothrom kit (co-packaged with ZymoGenetics Spray Applicator Kit)—1