Pyschiatric Disorders

Peer Comparisons Can Decrease Risky Prescribing Patterns

August 14, 2018

Over 9 months, the treatment arm prescribed 11.1% fewer quetiapine days per prescriber vs the control arm (P<.001; adjusted difference, −319 days; P<.001), which persisted over 2 years (15.6% fewer days; P<.001).

Harmful Internet "Challenges" and Teens: A Guide for Primary Care Providers

July 12, 2018

Discussions involving Internet challenges with children and adolescents should be as sensitive as those about sexuality and drug or alcohol use.

Palliative Care Reduces Odds of Suicide in Lung Cancer Patients

June 22, 2018

Only 20% of the patients who died by suicide had a palliative care encounter, compared with 57% among lung cancer patients whose cause of death was not suicide.

Children's hospital visits for suicide ideation and attempts are increasing

May 16, 2018

The percentage of patients seen at children's hospital for suicidal ideation (SI) and suicide attempts (SA) more than doubled between 2008 and 2015.

Sleep Apnea Rarely Investigated in Older Adults

May 16, 2018

The researchers found that 56% of the participants who completed the sleep module were estimated to be at high risk of OSA.

Time-Related Deployment Factors Predict Suicide Attempt Risk

April 19, 2018

The researchers found that the odds of SA during or after second deployment were increased among soldiers whose first deployment occurred within the first 12 months of service versus after 12 months and among those with a DT of 6 months or less versus longer than 6 months.

Prenatal Exposure to SSRI Tied to Fetal Brain Development

April 10, 2018

Compared with both healthy controls and infants exposed to untreated maternal depression, significant gray matter volume expansion was seen in the right amygdala and right insula in SSRI-exposed infants in voxel-based morphometry.

Parent-child reading interventions have positive psychosocial effects

March 27, 2018

A meta-analysis reviewing the effect of parent-child book reading interventions revealed a positive correlation between such interventions and a broad range of beneficial psychosocial outcomes, including social-emotional competence, quality of life, and parenting competence.

Novel Therapy for Major Depressive Disorder Gets Breakthrough Designation

By February 08, 2018

The Breakthrough Therapy designation is intended to offer a potentially expedited development path and review for promising drug candidates.

Written Exposure Therapy Found to Be Effective for PTSD

January 24, 2018

The 24-week assessment showed the largest difference between treatments. The WET group had significantly fewer dropouts than the CPT group (4 versus 25).

Significant Links Between Depressive Symptoms and Mortality in CA Patients

January 23, 2018

The researchers found that greater depressive symptoms were associated with significantly shorter survival (hazard ratio, 0.868; P<0.001), higher rates of chemoradiation interruption (odds ratio, 0.865; P=0.010).

Study Reveals Why Women Leave Medicine More Often Than Men

January 05, 2018

More women are entering medical school but still there are more male doctors.

Vraylar Approved as Maintenance Treatment for Schizophrenia

By November 13, 2017

Results showed that cariprazine significantly delayed the time to relapse compared to placebo (P=0.0010). A total of 49.5% (n=49/99) of placebo treated patients relapsed vs. 29.7% (n=30/101) for the cariprazine treated patients.

Psychosocial Intervention Improves Antidepressant Adherence

September 28, 2017

"The Treatment Initiation and Participation Program is an effective intervention to improve early adherence to pharmacotherapy," the authors write. "Improved adherence can promote improvement in depression."

Treatment Shows Efficacy in Binge Eating Disorder

August 04, 2017

In both studies, more participants on LDX versus placebo were categorized as improved on the Clinical Global Impressions-Improvement starting at week one.

More Sleep May Help Stave off Alzheimer's in Those At Risk

July 07, 2017

The researchers found an association between greater AD pathology and worse subjective sleep quality, more sleep problems, and daytime somnolence.

From Treatment to Training: 5 Uses of Virtual Reality in Healthcare

June 27, 2017

Virtual reality is much more than just a new form of entertainment, it is increasingly being used in a wide range of medical applications.

FDA Fast Tracks Drug for Hallucinations Disorder in Lewy Body Dementia

By June 19, 2017

Nelotanserin is a novel once-daily oral 5HT2A inverse agonist. The 5HT2A receptor has been associated with neuropsychiatric effects, including visual hallucinations.

Risks Associated with Lithium Use in Pregnancy Reevaluated

June 09, 2017

The study included information on 1,325,563 women enrolled in Medicaid. They gave birth between 2000 and 2010.

Antidepressant Linked to Accelerated Bone Loss

June 06, 2017

The researchers found that during venlafaxine treatment there was an increase in CTX and a decrease in P1NP, which was consistent with accelerated bone loss.

Depression Gender Disparities May Emerge Earlier Than Previously Thought

May 04, 2017

The study found the gender gap appears 2 to 3 years earlier than previously thought, from 13 to 15 down to age 12.

Chlorpromazine Dose-Response Investigated for Schizophrenia

By April 13, 2017

The gradual trend toward recommending lower dosages of chlorpromazine has arisen not due to trial based evidence, but rather clinical experience and consensus.

Overactive Bladder Tx Tied to Depressive Disorders

April 13, 2017

The researchers followed over 10,000 women for 3 years to assess the risk of depressive disorders associated with antimuscarinics.

Overactive Bladder Tx Tied to Depression in Women

By April 06, 2017

The researchers hypothesized that some antimuscarinics with "high lipophilicity, neutral polarity, or low molecular size still cross the blood-brain barrier and further affect neurotransmission in the brain," which could possibly trigger the depressive symptoms.

How Likely Are Teens to Seek Treatment for Eating Disorders?

March 27, 2017

Adolescents who met criteria for anorexia nervosa or bulimia nervosa were 2.4 and 1.9 times, respectively, more likely to seek treatment than adolescents who met criteria for binge-eating disorder.

Valbenazine for Tardive Dyskinesia

By March 21, 2017

Hauser, Robert A. et al. "KINECT 3: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Valbenazine for Tardive Dyskinesia"

Genetic Testing Abused by Patient with Factitious Disorder

By March 08, 2017

The patient presented with complaints of increased muscle tone in her back muscles and the right side of her body starting in adolescence.

Concussion Frequency, Symptoms Differ Between the Genders

March 03, 2017

Female athletes appear to be more likely than males to suffer concussions during their careers on the field, according to a new study by researchers at Columbia University, New York.

Report Outlines Screening and Treating Pediatric Sexual Assault

February 28, 2017

Pediatricians should be comfortable with treating and screening for sexual assault, and they should know where to send their teenage patients for any additional help, according to a clinical report from the American Academy of Pediatrics (AAP) published online in Pediatrics.

AAP: New Laws Do Not Denote Marijuana Use as Benign

February 28, 2017

The American Academy of Pediatrics (AAP) has published guidance to challenge any perception that marijuana is safe, even as 29 states allow its use.