Pruritus And Dry Skin

Mean Cumulative Lifetime Prevalence of Eczema 9.9%

December 04, 2018

The mean cumulative lifetime prevalence of atopic eczema is 9.9%, according to a research letter.

Upadacitinib Improves Pruritus in Moderate to Severe Atopic Dermatitis

November 19, 2018

Upadacitinib, a selective janus kinase-1 inhibitor, was associated with early improvements in pruritus in patients with moderate to severe atopic dermatitis.

Dupilumab Beneficial in Adolescent Patients With Moderate-to-Severe Atopic Dermatitis

By September 18, 2018

The Phase 3 trial enrolled 251 patients aged 12-17 years old with moderate-to-severe atopic dermatitis, whose disease was not adequately controlled by prescription topical medications or for whom topical treatment was medically inadvisable.

High Patient Burden With Moderate-to-Severe Atopic Dermatitis

July 06, 2018

Many patients with moderate/severe atopic dermatitis have inadequate disease control

Shower Cream, Body Lotion Combo Improves Atopic Dry Skin

May 15, 2018

Both products reduced clinical dryness, roughness, redness, cracks, tingling, and itch, according to the dermatologist, and increased feelings of soothing, smoothness, and softness, according to the participants.

No Clinical Benefit Seen for Bath Emollients in Childhood Eczema

May 03, 2018

POEM scores didn't meet minimal clinically important difference after adjustment for confounders

Methotrexate, Azathioprine Examined in Moderate-to-Severe Atopic Dermatitis

December 26, 2017

For up to five years as maintenance treatments for moderate-to-severe atopic dermatitis

Phase 3 Results Show Further Efficacy of Novel Plaque Psoriasis Tx

By December 04, 2017

At 16 weeks, 73% of risankizumab patients achieved PSAI 90 vs. 2% of the placebo patients and sPGA 0/1 was reached by 84% of riskanizumab patients vs. 7% of placebo patients (P<0.001).

Survey Shows Atopic Dermatitis Often Inadequately Controlled

December 01, 2017

The control rate increased with current AD severity and was 53.4% among patients receiving immunosuppressants and 83.4% among patients receiving systemic corticosteroids.

Some Prescription-Strength Meds May Be Easily Acquired Over-the-Counter

November 03, 2017

"Dermatologists and primary care physicians should be cognizant of any over-the-counter product that their patients are using," the authors of a JAMA report write.

When Is Systemic Treatment Appropriate for Atopic Dermatitis?

October 13, 2017

The authors recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy.

Crisaborole Safe for Long-Term Treatment of Atopic Dermatitis

October 11, 2017

Researchers assessed the long-term safety results from a multicenter, open-label, 48-week safety study of 517 patients ≥2 years of age with mild to moderate AD who continued crisaborole treatment after completing a 28-day phase 3 pivotal study.

Tuberculosis Vaccine May Carry Dermatological Benefits for Newborns

September 25, 2017

There was a significant difference in the effect of neonatal BCG vaccination between children with atopic predisposition and children without atopic predisposition.

Dupixent Improves Disease Severity, Skin Clearing in Atopic Dermatitis

By September 20, 2017

The data indicated 59% of patients given Dupixent weekly with topical corticosteroids and 63% of patients given Dupixent every 2 weeks with topical corticosteroids achieved EASI-75 vs. 30% of patients given placebo with topical corticosteroids (P<0.0001).

AAP Publish First Guidance on Tattooing, Piercing for Adolescents

By September 18, 2017

These can occur from contamination of the inks or diluents used for tattooing.

EpiCeram Now Available as Quad Pack Airless Pumps

By August 16, 2017

EpiCeram contains a balanced ratio of ceramides, free fatty acids, and cholesterol, which are essential lipids for total skin barrier repair; they mimic the lipid concentration found in the skin.

Does Early Probiotic Supplementation Reduce Eczema, Asthma Development?

August 08, 2017

The researchers found that the estimated cumulative incidence of eczema was 30.9 and 28.7% in the control and LGG arms at 2 years of age, respectively.

House Dust Mites May Induce lgE Sensitization to Antigens for Some

July 28, 2017

Researchers used IgE immunoblotting to analyze plasma samples from 179 atopic dermatitis patients for IgE-reactivity to a panel of micro-arrayed house dust mites allergen molecules.

Out-of-Pocket Spending for Topical Steroids Investigated

May 02, 2017

The researchers found that patients' out-of-pocket spending for topical steroids was $333.7 million. There was a 226.5% increase in total annual spending, from $237.6 million to $775.9 million.

Dupixent Approved for Moderate-to-Severe Atopic Dermatitis

By March 28, 2017

Dupixent, a human monoclonal antibody, works by inhibiting the overactive signaling of IL-4 and IL-13 proteins, which are believed to play a major role in the persistent inflammation in atopic dermatitis.

Emollient Use in Pediatric Atopic Dermatitis May Up Phthalate Levels

March 21, 2017

Children with frequent use of emollients generally had higher phthalate metabolite and paraben levels than uncommon users, reaching statistical significance for some LMW phthalates and parabens.

Addition of Antibiotics to Mild Eczema Tx Assessed in Children

March 15, 2017

The team found no significant differences between the three groups of children who received topical steroid, emollient, or placebo in terms of Patient Oriented Eczema Measure scores.

Nemolizumab for Atopic Dermatitis

By March 02, 2017

Ruzicka, Thomas et al. "Anti-Interleukin-31 Receptor A Antibody for Atopic Dermatitis"

Atopic Dermatitis May Impact Intradermal Flu Vaccine Efficacy

February 14, 2017

Reduced immune response after intradermal vaccination among patients colonized with S. aureus

Review of Moisturizer Efficacy in Eczema

By February 09, 2017

Among patients with eczema, most moisturizers showed some benefit but better results were seen when used with topical active treatment, according to a Cochrane Review.

Topical Steroid Tridesilon Now Available

By January 18, 2017

Tridesilon (desonide) Cream, 0.05%, has been made available by Encore Dermatology. This low-potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Prophylactic Moisturizing May Help Protect Infants from Atopic Dermatitis

By December 05, 2016

Daily application of petroleum jelly for the first 6 months of an infant's life can provide effective protection against atopic dermatitis, equating to a cost benefit of $353 per quality-adjusted life year (QALY).

Wet Wrap Therapy for Atopic Dermatitis: Is It Effective?

November 14, 2016

Wet wrap therapy may pose higher risk of local infections than topical steroids

New Treatment Option for Patients with Atopic Dermatitis

By October 13, 2016

This prescription-only lotion is indicated to manage and relieve the burning, itching and pain experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis.

Alitretinoin Evaluated in Chronic Hand Eczema

August 11, 2016

Alitretinoin treatment aids in normalizing expression of barrier genes and proteins in patients with chronic hand eczema (CHE), according to a study published online in the British Journal of Dermatology.