Poisoning/overdose

Similar Outcomes for Transplant With Overdose-Death Donors

April 17, 2018

The researchers found that ODDs accounted for 1.1 and 13.4% of donors in 2000 and 2017, respectively. ODDs were more likely to be white and aged 21 to 40 years (85.1 and 66.3%), to be hepatitis C virus (HCV)-infected (18.3%), and to be increased-infectious risk donors (IRDs; 56.4%).

Cannabis Compound Transfers to Breast Milk

April 10, 2018

The researchers found that delta-9-tetrahydrocannabinol was detected at low concentrations at all the time points beyond time 0, but no metabolites were detected at any time point.

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

By April 06, 2018

A recent report from the U.S. Senate Permanent Subcommittee on Investigations detailed how subcommittee members found it 'easy' to find fentanyl, pay for it and have it shipped to anywhere in the U.S.

Surgeon General Issues Advisory on Importance of Naloxone

By April 05, 2018

In a statement released today, Surgeon General, Jerome M. Adams, MD, MPH, said, "It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home."

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

April 03, 2018

The largest overall rate increases were seen among deaths involving cocaine and synthetic opioids (52.4 and 100%, respectively), likely due to increases in illicitly manufactured fentanyl.

Scale of Online Marketplace for Marijuana Increasing

March 30, 2018

From 2005 to 2017, the subset of marijuana searches on Google indicative of shopping increased 199%: During June 2017 there were 1.4 to 2.4 million marijuana shopping searches.

Liquids in E-Cigarettes Are Heterogeneous, Frequently Toxic

March 29, 2018

The more chemicals in an e-liquid, the more toxic it was likely to be; in addition, vanillin was associated with elevated toxicity values. There was a correlation for the concentration of cinnamaldehyde and vanillin, but not triacetin, with toxicity.

Rise in Bug Spray-Laced Street Drug Overdoses Has Authorities Concerned

By March 21, 2018

The Indianapolis Emergency Medical Services have responded to dozens of KD-related overdose calls since January.

Significant variation in mortality trends in substance use disorders among US counties

March 15, 2018

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014.

Study Finds Heat-Not-Burn 'Smokeless Cigarettes' Release Toxic Chemical

March 14, 2018

"This study has shown that the iQOS system may not be as harm-free as claimed and also emphasizes the urgent need for further safety testing as the popularity and user base of this product is growing rapidly," the authors write.

Death Due to Substance Use Disorders, Self-Harm: U.S. Trends Examined

March 14, 2018

The researchers found that there was considerable variation among counties in mortality rates from alcohol use disorders, drug use disorders, self-harm, and interpersonal violence. At the national level, there were decreases in mortality rates for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014.

CDC: Increases in Opioid-Involved Overdoses in All Five U.S. Regions

March 07, 2018

Per quarter, this rate increased on average by 5.6%. Increases were seen in rates across demographic groups and all 5 U.S. regions; the largest increases were seen in the Southwest, Midwest, and West (about 7 to 11% per quarter).

Multistate <i>Salmonella</i> Outbreak Linked to Controversial Supplement

By February 21, 2018

A total of 28 people from 20 states have been infected with the outbreak strain of Salmonella.

Researchers Hope to Test Heroin Vaccine in Humans Soon

By February 14, 2018

Researchers investigated 20 different carrier protein/adjuvant combinations.

The "Tide Pod Challenge": A Bizarre Trend With Serious Health Consequences

By January 19, 2018

The trend, referred to as the 'Tide pod challenge' may seem unreal, but during the first 15 days of January the American Association of Poison Control Centers have already registered 39 cases of intentional consumption.

Walmart Offers Unique Opioid Disposal Solution With DisposeRx

By January 17, 2018

Packets contain a crosslinking polymer blend that, when added to the pill bottle with warm water, sequester any form of prescription drugs - including powders, pills, tablets, capsules, liquids or patches - into a non-divertible and biodegradable gel.

CDC: 2016 Data Show Drop in Life Expectancy in U.S.

December 21, 2017

Increase in rate of age-adjusted drug overdose deaths observed during same time period

Most Multi-Med Patients Have Not Discussed Possible Drug Interactions

November 30, 2017

In terms of who is responsible for talking to patients about possible drug interactions, 11, 26, and 63% felt that the pharmacist, doctor, and both doctor and pharmacist are responsible, respectively.

Performance-Enhancing Substances Sold Online May Contain Unapproved Ingredients

November 30, 2017

The researchers found that 23 of the 44 products marketed and sold as selective androgen receptor modulators contained 1 or more selective androgen receptor modulator.

Naloxone Effectiveness Compared by Route of Administration

November 28, 2017

Higher-concentration intranasal naloxone (2mg/mL) seems to have efficacy similar to that of intramuscular naloxone for reversal of opioid overdose, with no difference in adverse events.

Methamphetamine Heart Failure May Present New Phenotype

November 15, 2017

"Clinicians are seeing more heart failure with meth use, suggesting heart failure due to methamphetamine use could be a new epidemic," said lead author, Marin Nishimura, MD, in a statement.

Concerns About Kratom Prompt Statement from FDA Commissioner

By November 14, 2017

Kratom is plant that grows naturally in Thailand, Malaysia, Indonesia and Papua New Guinea. It has gained popularity in the U.S., with some marketers touting it as a "safe" treatment with broad healing properties.

Illicit Fentanyl Major Driver of Opioid Overdose Deaths in U.S.

November 01, 2017

Data from 10 states participating in the CDC's Enhanced State Opioid Overdose Surveillance program was used to describe opioid overdose deaths from July through December 2016 that tested positive for fentanyl; fentanyl analogs; or U-47700, an illicit synthetic opioid.

CDC Report Examines Tobacco Use By Industry, Occupation

October 30, 2017

The researchers found that 22.1% of working adults currently used any form of tobacco; 15.4, 5.8, 3, and 3.6% used cigarettes, other combustible tobacco, smokeless tobacco, and electronic cigarettes, respectively

Opioid Epidemic Declared Public Health Emergency

By October 27, 2017

Unlike a national emergency, which is what Mr. Trump has referred to the epidemic has, a public health emergency does not involved the release of any federal funds.

Walgreens Takes Steps to Make Life-Saving Drug More Accessible

By October 26, 2017

Narcan Nasal Spray, an opioid antagonist, is indicated for the reversal of known or suspected opioid overdose, including respiratory and/or central nervous system (CNS) depression.

AMA Addresses Physician Obligations Regarding Unsafe Drinking Water

October 25, 2017

Lessons learned from Flint could expedite resolution of future environmental health crises. Noting that distrust of scientific and governmental authorities must be overcome, community-level ethical protections can re-establish trust within the community.

Opioid Dependence Prevention Txs Compared in Head-to-Head Study

By October 18, 2017

Results found that all primary endpoints for non-inferiority of extended-release naltrexone group were met; retention in treatment (P=0.04), group proportion of total number of opioid-negative urine drug tests (P<0.001), days of heroin use (P<0.001) and days of other illicit opioids use (P<0.001).

Alcohol May Contribute to Premature Mortality in Psoriasis Patients

By October 17, 2017

The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).

CVVH + Hemoperfusion Effective in Severe Metformin-Associated Toxicity

October 17, 2017

Case report describes treatment of female patient who attempted suicide with metformin overdose