Poisoning & Drug Dependence

Significant variation in mortality trends in substance use disorders among US counties

March 15, 2018

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014.

E-Cigarette Use: More Harm Than Benefit?

March 15, 2018

Estimated 168,000 never-smoking young people could become daily smokers after starting e-cigs

Study Finds Heat-Not-Burn 'Smokeless Cigarettes' Release Toxic Chemical

March 14, 2018

"This study has shown that the iQOS system may not be as harm-free as claimed and also emphasizes the urgent need for further safety testing as the popularity and user base of this product is growing rapidly," the authors write.

Death Due to Substance Use Disorders, Self-Harm: U.S. Trends Examined

March 14, 2018

The researchers found that there was considerable variation among counties in mortality rates from alcohol use disorders, drug use disorders, self-harm, and interpersonal violence. At the national level, there were decreases in mortality rates for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014.

Cocaine/Marijuana May Up Mortality in Younger MI Patients

March 13, 2018

Cocaine and/or marijuana use present in 10.7% of myocardial infarction patients age ≤50 years

Certain Personality Traits Linked to Social Media Addiction

By March 12, 2018

Neuroticism increased the likelihood of addiction while conscientiousness had a decreasing effect. However, it was noted that in those with high levels of both neuroticism and conscientiousness, being a stressful and anxious person could override conscientiousness, and in-turn, control over social media usage.

Does Marijuana Use Impact Kidney Function?

March 09, 2018

Researchers compared current and past marijuana use to never users

Pediatric Airflow Obstruction and Tobacco Smoke Exposure: Is There a Link?

March 09, 2018

Serum cotinine level was not significantly associated with airflow obstruction in the multivariate analysis with both exposures included as covariates (adjusted odds ratio, 1.07; 95% confidence interval, 0.94 to 1.21); there was no correlation in children with asthma or those without asthma.

CDC: Increases in Opioid-Involved Overdoses in All Five U.S. Regions

March 07, 2018

Per quarter, this rate increased on average by 5.6%. Increases were seen in rates across demographic groups and all 5 U.S. regions; the largest increases were seen in the Southwest, Midwest, and West (about 7 to 11% per quarter).

One Year On: Assessing the Effects of a Menthol Cigarette Ban

March 06, 2018

The researchers found that before the ban, 59.7% of menthol smokers said that they would switch to or only use nonmenthol cigarettes; at follow-up, only 28.2% had done so.

Study Reveals High Excretion of Carcinogenic Metabolites Among Teen E-Smokers

March 05, 2018

The researchers found that, compared with e-cigarette-only users, dual users had significantly higher urine excretion of metabolites of benzene, ethylene oxide, acrylonitrile, acrolein, and acrylamide (all P<0.05).

New Scale May Help Identify Patients Addicted to Tanning

March 05, 2018

The researchers found that tanning addiction was positively associated with being female, not being in a relationship, extroversion, neuroticism, anxiety, and obsessive-compulsiveness. New Screening Tool Developed to Assess Tanning Addiction

Sublocade Now Available for Moderate-to-Severe Opioid Use Disorder

By March 01, 2018

Sublocade is intended for use as part of a complete treatment program that includes counseling and psychosocial support.

CDC Breaks Down Figures for Smoking Prevalence During Pregnancy

February 28, 2018

The researchers found that 7.2% of women who gave birth in 2016 smoked cigarettes during pregnancy. The prevalence of smoking was highest for women aged 20 to 24 years, followed by those aged 15 to 19 and 25 to 29 years.

Have Medical Marijuana Laws Led to Increased Use in Teens?

February 28, 2018

The researchers found that none of the 11 studies included in the meta-analysis found significant estimates of pre-post MML changes in marijuana use prevalence among adolescents compared with changes in non-MML states over the same time period.

Most E-Cigarette Aerosol Concentrations Exceed Current Toxic Metal Limits

February 27, 2018

The researchers found that median metal concentrations were higher in samples from the aerosol and tank, compared to the dispenser (all P<0:001), for aluminum, chromium, nickel, lead, and zinc.

Off-Label Baclofen Use for Alcohol Use Disorders: Is it Effective?

By February 26, 2018

Data showed a significant effect on abstinence rates with the use of baclofen (odds ratio [OR] 2.67, 95% CI: 1.03, 6.93) but no other significant effects on treatment efficacy (heavy drinking days SMD -0.26, 95% CI: -0.68, 0.15) or mechanism of action (craving SMD: -0.13, 95% CI: -0.36, 0.09) were seen.

Multistate <i>Salmonella</i> Outbreak Linked to Controversial Supplement

By February 21, 2018

A total of 28 people from 20 states have been infected with the outbreak strain of Salmonella.

Study Belies Common Notion That Opioid Patients Fail Outpatient Tapers

February 21, 2018

The researchers found that 38% of the 82 enrolled patients did not complete a 4-month follow-up survey and were considered to have dropped out. There was a negative correlation for depression and a positive correlation for baseline marijuana use with study completion.

Death Risk Assessed With Contemporary Tobacco Product Use

By February 21, 2018

For current non-daily cigarette smokers, there were statistically significant associations with death from lung cancer, oral cancer, circulatory death, cardiovascular death, cerebrovascular death (stroke), and chronic obstructive pulmonary disease.

Researchers Hope to Test Heroin Vaccine in Humans Soon

By February 14, 2018

Researchers investigated 20 different carrier protein/adjuvant combinations.

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Targeting Harm Perceptions Could Cut Teen E-Cigarette Use

February 12, 2018

Perceived harm from secondhand e-cigarette vapor showed similar patterns. Adolescents who use e-cigarettes are more likely to initiate using tobacco products than those who do not use e-cigarettes.

Spouse of Person With Alcohol Use Disorder at 'Rapid' Risk

February 08, 2018

After a first marriage to a spouse without AUD, the hazard ratios for AUD were 7.02 and 9.06, respectively, in women and men with a second marriage to a spouse with AUD.

FDA Analysis Shows Kratom Not "Just a Plant"

By February 07, 2018

Kratom should not be used to treat medical conditions, nor should it be used as an alternative to prescription opioids.

Motivation Has Little Overall Effect in Reducing Alcohol Consumption

February 05, 2018

Motivation did not have an effect on further reducing consumption, with the difference-in-differences effect actually suggesting average increase.

Do the Benefits of Smoking Cessation Tx Decrease Over Time?

By January 31, 2018

Benefits of smoking cessation medications decline over the first year.

Premature Unusual Amnesia Syndrome Linked to Substance Use

January 30, 2018

"To our knowledge this report is the first to associate fentanyl with this amnestic syndrome," the authors write.

How E-Cigarette Smoke May Damage DNA, Inhibit Repair

January 30, 2018

"These results indicate that nicotine nitrosation occurs in vivo in mice and that e-cigarette smoke is carcinogenic to the murine lung and bladder and harmful to the murine heart," the authors write.

Smokers Display Distorted Temporal Perception of Health Consequences

January 29, 2018

For both smokers and nonsmokers, the onset time estimates for mild conditions were associated with self-perceptions of risk and fear level of developing smoking-related conditions.