PCV13 in Adults Under 65 With Diabetes May Avert Pneumonia Hospitalizations

October 09, 2018

PCV13 in adults age <65 years with diabetes could reduce a substantial number of pneumonia hospitalizations.

Positive Results for Zerbaxa in Phase 3 Study of Ventilated HABP, VABP Patients

By September 11, 2018

The full findings from the study will be presented at a future scientific conference; Merck plans to include the data in a supplemental New Drug Application for Zerbaxa which will be submitted to the Food and Drug Administration.

Omadacycline Gets FDA Committee Nod for Skin Infections, Pneumonia

By August 09, 2018

The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.

Is Short-Course Antibiotic Treatment for CAP Effective?

By July 11, 2018

To investigate what impact antibiotic treatment duration has on CAP outcomes, researchers from the Warren Alpert Medical School of Brown University conducted a search of various databases for studies comparing the safety and efficacy of treatment regimens lasting ≤6 days (short) and ≥7 days (long).

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

By May 24, 2018

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

Positive Results Announced for Pleuromutilin Antibiotic in CABP

By May 22, 2018

In the LEAP 2 study (N=738), patients with moderate CABP received either oral lefamulin 600mg every 12 hours for 5 days or oral moxifloxacin 400mg once daily for 7 days

Omadacycline Granted Priority Review for CABP, Skin/Skin Structure Infections

By April 05, 2018

Omadacycline is an investigational, once-daily, broad-spectrum aminomethylcycline antibiotic that is related to tetracyclines.

Opioid Use May Increase the Risk for Invasive Pneumococcal Disease

February 13, 2018

Strongest associations seen for opioids that were long acting, of high potency, and used at high doses

Bacterial Transmission from Guinea Pigs Linked to Three Cases of CAP

September 08, 2017

Three cases of community-acquired pneumonia reported after exposure to ill guinea pigs

<i>Legionella</i> Poses a Potentially Deadly Risk to Patients in Health Care Facilities

By June 06, 2017

The analysis found that 3% of Legionnaires' disease cases are definitely associated with a health care facility while 17% were deemed as possibly associated with a health care facility.

Antibiotic Failure Rates Investigated in Community-Acquired Pneumonia

By May 22, 2017

The researchers found that the total treatment failure rate was 22.1%, defined as either the need to refill antibiotic prescriptions, antibiotic switch, ER visit or hospitalization within 30 days of receiving initial antibiotic prescription.

CDC: Prescription Drug Abuse Mortality Rates Skewed by Death Certs

April 27, 2017

More than half (54%) of a series of drug-related unexplained deaths in Minnesota between 2006 and 2015 listed pneumonia as the cause of death.

Vibativ Efficacy Against Difficult-to-Treat Bacteria Compared with Other Antibiotics

By April 25, 2017

The favorable in vivo results further confirm the ongoing use of Vibativ for its use in HABP/VABP due to S. aureus, including MRSA.

Certain Antidiabetic Agents Linked to Increased Pneumonia Risk

By April 17, 2017

Results showed that compared with current use of metformin + sulfonylurea, the use of thiazolidinediones + metformin was associated with an increased risk of CAP.

Benzodiazepine Use Among Alzheimer's Patients May Up Pneumonia Risk

By April 10, 2017

Analysis found that the use of benzodiazepines was significantly associated with an increased risk of pneumonia (aHR 1.28, 95% CI: 1.07-1.54) but not for the similarly acting non-benzodiazepines (aHR 1.10, 95% CI: 0.84-1.44).

Novel Tetracycline Goes Head-to-Head with Moxifloxacin in Pneumonia Study

By April 04, 2017

The study met the primary and secondary endpoints, showing that omadacycline is non-inferior to moxifloxacin for the treatment of CABP.

Amoxicillin vs. Macrolide Rx Characteristics in Pediatric CAP

March 09, 2017

For children with community-acquired pneumonia (CAP), patient and nonclinical characteristics are associated with receipt of macrolides and broad-spectrum antibiotics versus amoxicillin, according to a new study.

Do Inhaled Corticosteroids Up Pneumonia Risk in Children with Asthma?

February 27, 2017

No increased risk of pneumonia; no link for ICS with risk of pharyngitis, otitis media, sinusitis

Two Asthma Meds Show Promise in Halting Lethal Pneumonia

February 27, 2017

A mice model demonstrated that treating severe influenza with Singulair or Accolate may prevent severe pneumonia.

Does Pneumococcal Vaccination Reduce Pneumonia Risk in COPD?

By January 26, 2017

A Cochrane review found that polyvalent pneumococcal vaccines offered significant protection against community-acquired pneumonia (CAP) in chronic obstructive pulmonary disease (COPD) patients, however, the evidence did not show that vaccination lowered the risk of confirmed pneumococcal pneumonia.

Which Condition Ranks Highest for Hospital Readmission?

By January 23, 2017

Of the medical conditions tracked by the government to measure quality of care and guide pay-per-performance reimbursements, sepsis accounted for significantly more hospital readmissions and associated costs than any of the tracked conditions.

Antibiotic Safety, Efficacy Assessed in Community-Acquired Pneumonia

By January 12, 2017

Findings from a U.S. claims-based retrospective study published in Hospital Practice call for the development of more effective antimicrobial treatments that have a reduced adverse events burden for patients with community-acquired pneumonia (CAP).

Which Alzheimer's Drug Is Linked to the Highest Pneumonia Risk?

By November 21, 2016

Researchers aimed to compare the risk of pneumonia with the use of donepezil, oral rivastigmine, transdermal rivastigmine, galantamine, and memantine.

Route of Administration for Post-discharge Antibiotics Compared in Complicated Pneumonia

November 17, 2016

For children with complicated pneumonia, peripherally inserted central venous catheter (PICC) and oral antibiotic administration post-discharge have similar rates of treatment failure.

FDA Committee Votes in Favor of Powerful Macrolide Antibiotic

By November 08, 2016

The Food and Drug Administration (FDA)'s Antimicrobial Drugs Advisory Committee (AMDAC) voted 7-6 that the benefits of solithromycin outweigh the risks associated with this treatment for community-acquired bacterial pneumonia (CABP).