Ingesting nonsteroidal anti-inflammatory drugs (NSAID) at a higher potency level may cause nausea, vomiting, epigastric pain, diarrhea, tinnitus, headache, and even gastrointestinal bleeding; pediatric patients are also at greater risk of developing NSAID-associated renal injury.
An investigational transdermal cannabidiol gel was well-tolerated and consistently effective for adults with focal epilepsy.
Migraine with aura is associated with an elevated risk for incident atrial fibrillation, according to a new study.
In Study 303 (N=1375), rimegepant, an oral calcitonin gene-related peptide (CGRP) receptor antagonist, achieved statistical significance in 2 co-primary endpoints: pain freedom and freedom from most bothersome symptom (MBS).
Adult doses for migraine and headache treatments including barbiturates, ergot alkaloids, and NSAIDs.
A comparative chart of narcotic analgesics including formulations, strengths, and dosing intervals.
The Agency conducted testing on 26 separate kratom products which revealed levels of nickel and lead considered not safe for human consumption.
A study by the National Survey of Drug Use and Health (NSDUH) found that from 2002-2014 the proportion of adults aged 50 to 64 who reported cannabis use in the past year more than tripled from 2.9% to 9.0%. Among adults age 65 or older, there was more than a ten-fold increase (from 0.2% to 2.1%).
While approved in Europe, Asia and Latin America, tianeptine is an unscheduled pharmaceutical agent in the US that has been linked to serious adverse events, including death, when used for recreational purposes.
Compared with being attracted only to the opposite sex, being attracted mostly to the opposite sex or being equally attracted to both sexes correlated with higher odds for past-year opioid misuse (adjusted odds ratios, 2.15 and 1.78, respectively).
The vote was taken in a joint meeting of the Anesthetic and Analgesic Drug Products Advisory Committee and Drug Safety and Risk Management Advisory Committee.
Reports of pump failure, dosing errors, as well as other possible safety issues have prompted the Agency to issue the alert to make prescribers aware of the dangers associated with using medications not approved for intrathecal use.
Researchers found that the naloxone nasal spray Narcan was chemically stable for 10 months after its labeled expiration date and that the naloxone injection Evzio was chemically stable for at least 1 year after its listed expiration date.
Researchers examined the correlation between surgical procedures that require general anesthesia before primary school entry and child development in a retrospective sibling-matched cohort study, including sibling pairs aged 5 to 6 years with the same birth mother.
The sublingual formulation of sufentanil offers a new treatment option for patients with nothing by mouth (NPO) status and patients with difficult IV access.
The new software enables patients to fine-tune the power level and modify programs that were pre-programmed by their clinician to control pain.
The treatment is designed to deliver pain relief directly to the site of tissue injury, thereby potentially reducing the need for systemically administered pain medications.
The patient's past medical history was significant for chronic kidney disease (stage 5) on nightly peritoneal dialysis, type 2 diabetes mellitus, peripheral neuropathy, gastroesophageal reflux disease, hypertension, and chronic pain.
Patients with SLE who experienced high pain levels and had a visit to the emergency department the previous year were more likely to use opioids.
There is $60 million earmarked for infants who are born drug-dependent and authorization for programs that place drug offenders into treatment instead of in prison.
Recommendations on the use of these agents in this patient population were published in a Views and Perspectives paper in the journal Headache.
The training has information on how to use several products including a nasal atomizer, Narcan Nasal Spray and Evzio.
The researchers found that 83% of the patients required no narcotic medication postoperatively. Preoperative opioid use significantly predicted postoperative narcotic requirement.