Drugs in the Pipeline
The update was based on data from the COV-BARRIER study.
In patients who were hospitalized with severe coronavirus disease, treatment with lopinavir-ritonavir did not provide a substantial benefit beyond standard care.
The EUA was issued based on 4 randomized controlled clinical trials that evaluated the efficacy and safety of Actemra in more than 5500 hospitalized patients with COVID-19.
The study, which was fully remote and contactless, aimed to evaluate whether early treatment with fluvoxamine reduced the likelihood of clinical deterioration and disease severity in patients with mild COVID-19 illness.
The patient, who had a history significant for cerebral palsy, seizures, and chronic constipation, had presented complaining of 3 days of fever, nausea, vomiting, and anorexia.
The patient, a 74-year-old female, presented to the ER after experiencing a low grade fever, cough, and shortness of breath for 2 days.
The first US clinical trial to assess the efficacy and safety of an investigational broad-spectrum antiviral agent, remdesivir (Gilead Sciences, Inc.), for the treatment of coronavirus disease 2019.
Recommendations on the management of coronavirus disease 2019 (COVID-19) were recently released by the National Institutes of Health (NIH) to help guide clinicians caring for patients with COVID-19.
Safety Alerts and Recalls
The use of e-cigarette products has been associated with several cases of severe pulmonary disease, according to the Centers for Disease Control and Prevention (CDC). In an official health advisory, the CDC stated that 215 possible cases have been reported across 25 states, with additional suspected cases still under investigation. One death has also been…
Use of home oxygen is associated with reduced physical function in patients with either COPD or idiopathic pulmonary fibrosis.