News
Gavreto Gets Accelerated Approval for RET-Altered Thyroid Cancers
The approval was based on data from the phase 1/2 ARROW trial which evaluated the efficacy and safety of Gavreto in patients with RET-mutant MTC.
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Slideshow
Clinical Challenge: Red, Itchy Rash of the Upper Body
A 50-year-old man is referred for evaluation of a rash first noted approximately 2 months ago. He states that the rash is itchy and is accentuated by rubbing and applying pressure. Despite a 2-week course of cetirizine, the condition has not improved. The patient is currently prescribed a thiazide diuretic to control his hypertension. Examination…
News
Novel Treatment Gains Accelerated Approval for Relapsed/Refractory Neuroblastoma
Approval was based on results from two phase 2 single-arm, open-label trials that demonstrated overall response rate and duration of response.
News
RSNA: Neurologic Complications of COVID-19 Examined
In patients with critical findings identified on neuroimaging, most common comorbidities were hypertension, diabetes
News
FDA Approves Oxlumo for Primary Hyperoxaluria Type 1
Lumasiran is an investigational ribonucleic acid interference therapeutic that inhibits hepatic production of oxalate by targeting hydroxyacid oxidase 1.
News
First Treatment for Progeria Gets FDA Approval
Zokinvy works by preventing farnesylation and subsequent accumulation of progerin and progerin-like proteins in the inner nuclear membrane.
Drugs in the Pipeline
Long-Acting Cabotegravir Gets Breakthrough Therapy Status for HIV PrEP
Results from the final analysis showed that cabotegravir was 66% more effective than FTC/TDF in preventing HIV acquisition.
Features
A Review of Treatments for HFrEF and Expert Q&A
Despite substantial advances in therapeutic options for HFrEF, significant gaps remain in the use of guideline-directed medical therapy in these patients.
News
USPSTF Finds Evidence Lacking for Child HTN Screening
I statement based on lack of studies examining benefits and harms of screening, impact of treatment on outcomes in adulthood
News
FDA Identifies Most Needed Meds to Address Urgent Medical Conditions
This action was in response to an executive order issued on August 6, 2020 aimed at protecting the public against outbreaks of emerging diseases and chemical, biological, radiological, and nuclear threats.
