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Novartis announced data from its Phase 3 study of ACZ885 (canakinumab) for the treatment of children with active systemic juvenile idiopathic arthritis (SJIA).

There was a correlation for non-rhinovirus pathogens with increased absolute risk of treatment failure by 13.1%; specifically, by 8.8, 24.9, and 34.1% for respiratory syncytial virus, influenza, and parainfluenza, respectively.

Children and adolescents who are obese are more likely to develop severe forms of asthma.

For patients with severe eosinophilic asthma, treatment with mepolizumab, a monoclonal antibody against interleukin 5, is effective at reducing clinically significant exacerbations.

Clinical practice guideline addresses 6 emerging questions around COPD management.

The submission was based on data from the double-blind, placebo-controlled VOYAGE trial.

The BLA submission is supported by data from the PATHFINDER clinical program.

High doses of inhaled corticosteroids were associated with lower levels of eosinophils, which may interfere with the recommendation of some monoclonal antibodies in asthma treatment.

Active eosinophilic esophagitis appears to be associated with lower lung function and increased asthma severity in children with comorbid asthma.

Colchicine use had declined 27% by 2019 compared with before the 2010 price increase.