The approval was based on data from three phase 3 trials that evaluated the efficacy and safety of upadacitinib in patients 12 years of age and older with moderate to severe atopic dermatitis who are candidates for systemic therapy.
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Findings may help with decision-making in this high-risk patient population.
The updated labeling is based on results from a safety management cohort from the ZUMA-1 study.
Rilzabrutinib is an oral Bruton tyrosine kinase inhibitor currently in development for a number of immune-mediated diseases.
The FDA has approved Zeposia® (ozanimod) for moderately to severely active ulcerative colitis in adults.
Ascorbic acid level testing confirmed severe deficiency (<0.1mg/dL).
Does the allergic status of patients with asthma affect asthma exacerbation rates and outcomes following COVID-19?
In a study, the calcineurin inhibitor tacrolimus proved to be noninferior to intravenous cyclophosphamide.
The approval was based on data from the phase 3 JADE clinical trial program, which included the JADE MONO-1, JADE MONO-2, and JADE COMPARE trials.
Previous studies have shown that GLP-1RAs demonstrate a protective effect by attenuating bronchial hyperresponsiveness.