“Children with AFL had significantly higher total blood and bronchoalveolar lavage (BAL) eosinophil count, total IgE, [immunoglobulin E] and greater number of positive allergen specific serum IgE,” the investigators noted.
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Investigators assessed the annualized asthma exacerbation rate (AAER) and the annualized rate of asthma exacerbations requiring hospitalization over 52 weeks.
The study included 223 patients with moderate-severe disease based on baseline scores.
“A needle-free option for administering epinephrine would be used more quickly after symptoms developed and would be easier to use versus an injectable device.”
The observational study that enrolled 2847 adult patients with severe asthma receiving maintenance systemic corticosteroids, biologics, or uncontrolled on high-dosage inhaled corticosteroids and additional controllers.
The vote was mixed when the data was reviewed for younger patients.
Dupixent single-dose prefilled pens feature a hidden needle and single-press auto-injection.
The MESSINA study included patients 12 to 65 years of age with symptomatic and histologically active EoE.
Can patients with allergic asthma benefit from omalizumab even if they fall outside the criteria put forth in the approved recommended dosing table?
Post hoc analysis of a real-world COPD trial assessed the effect of triple therapy in reducing exacerbations in patients with higher vs lower eosinophil levels.