The application is supported by data from the pivotal phase 3 PHALCON-EE trial which compared the efficacy and safety of vonoprazan to lansoprazole in patients with erosive esophagitis.
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Osteoarthritis is the leading form of arthritis and growing. With people living longer, by 2030 osteoarthritis is expected to become the single greatest cause of disability globally.
Adults receiving proton pump inhibitors have increased risk for acute kidney injury requiring dialysis following cardiac surgery
Each individual component of the composite outcome was significantly higher among statin users
Increased incidence of CAP was noted in stroke patients using PPIs.
Study is the largest to explore this potential safety issue to date.
Bylvay is an oral reversible inhibitor of the ileal bile acid transporter.
Proton pump inhibitors, beta-blockers, antimetabolites linked to infection with antibiotic-resistant bacteria
However, treatment with proton pump inhibitors is not associated with risk for incident diabetes in the general population