Tecarfarin is a novel oral vitamin K antagonist with a similar mechanism of action to warfarin, though it is metabolized differently.
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The FDA has approved updated labeling for Epclusa (sofosbuvir/velpatasvir), Harvoni (ledipasvir/sofosbuvir) and Vosevi (sofosbuvir/velpatasvir/voxilaprevir) to include updated information regarding treatment of patients with hepatitis C virus (HCV) who have severe renal impairment including those with end stage renal disease who are on dialysis.
Bardoxolone methyl does not reduce the risk of end-stage renal disease (ESRD) or cardiovascular death in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease.
For patients with end-stage renal disease (ESRD), daily cocoa flavanol (CF) ingestion alleviates acute and chronic hemodialysis (HD)-induced vascular dysfunction, according to a study published online in the Clinical Journal of the American Society of Nephrology.
For women with end-stage renal disease (ESRD), intensive hemodialysis is associated with improved pregnancy outcomes.
For patients with end-stage renal disease (ESRD) referred for coronary revascularization, coronary artery bypass grafting (CABG) is associated with a small decrease in long-term mortality compared with percutaneous coronary intervention (PCI)
The researchers found that an estimated 1% absolute increase in quarterly ILI correlated with a 1.5% increase and a 2.0% increase in relative mortality for quarters 4 and 1, respectively.
Canagliflozin decreases the risk of kidney failure in patients with chronic kidney disease and type 2 diabetes, according to a new study.
MK-2060 is an investigational monoclonal antibody designed to inhibit the activation of Factor XI and its ability to activate downstream proteins.
Lowering LDL cholesterol in patients with chronic kidney disease does not significantly benefit renal progression.