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For patients with end-stage renal disease (ESRD), daily cocoa flavanol (CF) ingestion alleviates acute and chronic hemodialysis (HD)-induced vascular dysfunction, according to a study published online in the Clinical Journal of the American Society of Nephrology.

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The labeling for Onglyza (saxagliptin; Bristol-Myers Squibb) has been updated to include data from two clinical trials: a study of Onglyza in patients with moderate to severe renal impairment or end-stage renal disease (ESRD) and a second comparator study of Onglyza + metformin versus glipizide + metformin.

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Long-term daily use of fenofibrate is beneficial for patients with type 2 diabetes and moderate renal impairment and is not associated with an increase in drug-related safety concerns compared with those with mild renal impairment.