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Shortly after an EUA was issued, Genentech announced that tocilizumab (marketed under the brand name Actemra) was in shortage.

The Simplist ready-to-administer prefilled syringes require no assembly or point-of-care preparation.

The EUA was issued based on 4 randomized controlled clinical trials that evaluated the efficacy and safety of Actemra in more than 5500 hospitalized patients with COVID-19.

Findings showed that the trial did not meet statistical significance on the primary endpoint.