A minimally invasive treatment for retinal detachment leads to favorable outcomes, according to a study published in Ophthalmology.
In this randomized controlled trial, both mortality and retinopathy of prematurity (ROP) type 1 occurred more often in preterm infants treated with myo-inositol than in those treated with placebo.
The planned enrollment was 1760 participants; however, the trial was terminated early due to a statistically significantly higher mortality rate in the myo-inositol group.
The approval was based on data from a randomized, double-masked, placebo-controlled study of 90 pediatric patients aged 2 to < 18 years with active JIA-associated non-infectious uveitis.
The NDA includes data from one Phase 2 and two Phase 3 clinical trials (STRIDE 1 and STRIDE 2) involving ~2000 individuals with dry eye disease.
Participants with a high MeDi score showed a significantly reduced risk for incident advanced AMD versus participants with a low score (range, 6 to 9 vs 0 to 3) in the fully adjusted model using data for both the RS-I and Alienor Study (hazard ratio, 0.59).
Glaucoma treatment chart (alpha2-agonists, beta blockers, carbonic anhydrase inhibitors, cholinergic agonists, prostaglandin analogs).
Xelpros contains latanoprost, a prostaglandin F2α analogue that is believed to reduce IOP by increasing the outflow of aqueous humor.
Bacterial conjunctivitis treatment chart for topical medications.
Data from two Phase 3, multicenter, randomized, double-masked, placebo-controlled trials showed a greater proportion of patients treated with Inveltys having complete resolution of ocular inflammation.
The safety and efficacy of Oxervate was evaluated in 2 independent, double-masked, randomized, multicenter, controlled clinical trials involving patients with moderate to severe neurotrophic keratitis.
The approval was supported by year 2 data from the Phase 3 VIEW 1 and VIEW 2 trials that evaluated 2412 patients with wet AMD who followed a modified 12-week dosing schedule (doses at least every 12 weeks and additional doses as needed).
The woman couldn't recall how the contact lens got there or how long it was there, but her mother remembered that she had been hit in the eye with a shuttlecock during a game of badminton 28 years ago.
The new ocular drops contain carboxymethylcellulose (CMC) 0.5%, hyaluronic acid (HA), glycerin 0.9%, and other organic osmoprotectants.
A comparative dosing chart of prescription and over-the-counter (OTC) medications for allergic conjunctivitis treatment.
There were differences in steepest keratometry of 47.35 diopters in patients with DS vs 43.7 diopters in control subjects. There were also differences in corneal pachymetry of 503µm in patients with DS versus 545µm in controls.
Compared with children in the control group, children with amblyopia had a slower mean time to completion (P=.001), as did children with non-amblyopic strabismus (P=.002).
The trial included 594 individuals with open-angle glaucoma or ocular hypertension. Participants were randomized to receive 3 administration cycles (Day 1, Week 16 and Week 32) of Bimatoprost SR or twice daily timolol eye drops.
GPLSCD01 is an investigational treatment made up of ex vivo expanded autologous human corneal epithelial cells containing stem cells.
A U.K. university graduate with 17 years of education would be at least −1 dioptre more myopic, on average, than someone who left school at age 16 with 12 years of education.
In a clinical trial of 389 individuals with iris defects, 70% of patients reported a significant decrease in light sensitivity and glare.
The patients were 2 white men aged 52 and 85 years with metastatic cutaneous melanoma and a 68-year-old African-American man with metastatic adenocarcinoma of the lung. All 3 patients were receiving anti-PD-1 and anti-PD-L1 monoclonal antibody therapy.
Azasite, supplied as a 2.5mL solution, contains benzalkonium chloride. It is indicated for use in susceptible bacterial conjunctivitis.
All lesions respected the horizontal raphe, and the fovea was spared. A V-shaped hyperreflectivity of the outer nuclear layer was seen with OCT imaging, overlying discontinuities of the ellipsoid zone and interdigitation zone in smaller lesions.