Efficacy of Moisturizer, Estradiol Tablets Examined in Treating Vulvovaginal Symptoms

March 20, 2018

Similar reductions were seen for most bothersome symptom severity for all treatment groups over 12 weeks (estradiol, −1.4; moisturizer, −1.2; and placebo, −1.3).

Abaloparatide Followed by Alendronate Ups BMD in Postmenopausal Women

By March 19, 2018

At the 43-month endpoint, a total of 60.7% (307/506) of the abaloparatide followed by alendronate group had ≥3% increase in bone mass at all 3 sites (P<0.0001) vs. 24% (121/505) of the placebo followed by alendronate group.

Male Birth Control Pill Moves 'Step Closer' Following Safety Trial

March 19, 2018

Suppression of follicle stimulating hormone and luteinizing hormone was reported for all subjects in the P400mg group and 12 of 13 subjects in the C400mg group. No significant change was seen in mood.

Positive Results for Elagolix in Second Phase 3 Uterine Fibroid Trial

By March 14, 2018

Results - measured by the alkaline hematin method - found that at 6 months those in the combination group had 76.2% (P<0.001) clinical response compared to the elagloix along group, in which only 10.1% had a clinical response.

FDA Accepts NDA for Bio-Identical Combination Hormone Therapy

By March 09, 2018

TX-001HR is an investigational treatment for moderate-to-severe vasomotor symptoms due to menopause.

Hormone Replacement Therapies

March 06, 2018

Chart with different formulations and combination of drugs used to treat menopause.

Product Defect Leads to Recall of Hormone Replacement Therapy

By March 05, 2018

The recall was initiated due to a manufacturing defect.

Is Domperidone Effective for Increasing Breast Milk Volume?

March 05, 2018

The researchers identified 5 trials consisting of 194 women. Pooled analysis showed a moderate increase in breast milk volume of 88.3 mL/day with the use of domperidone versus placebo

Is It Safe for Women to Eat or Drink During Labor?

March 01, 2018

"Allowing women ad lib oral intake during labor does not increase adverse maternal or neonatal outcomes. It stands to reason that allowing such intake could increase patient satisfaction," the authors write.

Progestin-Only Contraceptives and Depression: Is There a Link?

By February 28, 2018

Study quality was graded according to the United States Preventive Services Task Force and the Cochrane Risk of Bias Tools.

CDC Breaks Down Figures for Smoking Prevalence During Pregnancy

February 28, 2018

The researchers found that 7.2% of women who gave birth in 2016 smoked cigarettes during pregnancy. The prevalence of smoking was highest for women aged 20 to 24 years, followed by those aged 15 to 19 and 25 to 29 years.

Impact of Asthma Medication on Fertility Examined in Women

February 27, 2018

No link to infertility for those with former asthma, or for those with asthma preventer medications

Menopausal Hormone Therapy May Aid in Reducing Spine Injury

February 23, 2018

The researchers found that, compared with never-users of HT, continuous users had a mean Cobb angle that was 4.0 degrees less, in minimally-adjusted models (P=0.01); in fully-adjusted models, the correlation was attenuated to 2.8 degrees (P=0.06).

Vaccination During Pregnancy Not Linked to Infant Hospitalization, Death

February 21, 2018

There was no correlation between infant hospitalization and maternal influenza (adjusted odds ratio, 1; 95% confidence interval, 0.96 to 1.04) or Tdap (adjusted odds ratio, 0.94; 95% confidence interval, 0.88 to 1.01) vaccinations.

Ulipristal Assessed in Symptomatic Uterine Leiomyomas

February 20, 2018

The researchers found that amenorrhea was achieved by 47.2, 58.3, and 1.8% of patients in the ulipristal 5mg and 10mg, and placebo groups, respectively.

Ready-to-Use Makena Formulation Approved to Reduce Preterm Birth Risk

By February 15, 2018

Makena was the first FDA-approved treatment option for pregnant women who have had prior spontaneous preterm birth.

Antihypertensive Use During Delivery Evaluated Among Preeclamptic Women

February 15, 2018

The researchers found that overall, 105,409 women received a hypertensive agent. Receipt of oral labetalol increased from 20.3% in 2006 to 31.4 percent in 2014 for all patients with preeclampsia.

Is There Any Link Between Ultrasound Exposure and Autism?

February 14, 2018

The ASD group had a shorter duration of ultrasound exposure than the typical development group during the first (290.4 versus 406.4 seconds) and second (1,687.6 versus 2,011 seconds) trimesters. Greater mean depth of ultrasonographic penetration was seen in the ASD group versus the developmental delay group in the first trimester (12.5 versus 11.6 cm).

Inhaled Nitric Oxide Examined for Lowering Neonate Mortality

February 09, 2018

The researchers identified 993 neonates (2.6%) who received iNO among 37,909 neonates in the study sample. A total of 971 patients were included in each of the two matched cohorts.

Has Family Integrated Care in the NICU Affected Outcomes?

February 08, 2018

For infants in the FICare group, the high-frequency exclusive breastmilk feeding rate at discharge was higher than that seen in those in the standard care group (70 versus 63%; P=0.016).

Fetal Risk After Pregnancy Exposure to Natalizumab Examined

February 08, 2018

And, natalizumab washout period is only predictor of relapse occurrence during pregnancy

USPSTF: Screening for Syphilis in Pregnant Women Beneficial

February 07, 2018

Draft recommendation indicates considerable net benefit to screening for syphilis infection

Prevalence of Fetal Alcohol Spectrum Disorder Examined in the U.S.

February 07, 2018

For fetal alcohol spectrum disorders, the conservative prevalence estimates varied from 11.3 to 50.0 per 1,000 children; the weighted prevalence estimates varied from 31.1 to 98.5 per 1,000 children.

Low-Carb Diets Linked to Increased Risk of Neural Tube Defects

February 06, 2018

First study to assess the effect of carb intake on neural tube defects, postfortification with folic acid

Toxic Plant Extract Shows Promise in Early Male Birth Control Studies

February 02, 2018

While the male hormonal birth control pill option is in clinical human trials and likely closer to market, it has several potential side effects: In addition to potentially causing weight gain and changes in libido.

Edurant Dosing Recommendations Updated for Pregnant HIV Patients

By February 02, 2018

Lower exposures of rilpivirine were observed during pregnancy, therefore viral load should be monitored closely.

To What Extent Can Postnatal Depression Impact Child Behavior?

February 02, 2018

For mothers with moderate, marked, and severe PND, the odds ratios for child behavioral disturbance were 2.22, 1.91, and 2.39, respectively.

Zika-Related Flaviviruses May Also Have Potential to Cause Congenital Infection

February 01, 2018

Efficient replication was reported for West Nile virus and Powassan virus in second-trimester human maternal (decidua) and fetal (chorionic villi and fetal membrane) explants, while less efficient replication was seen for CHIKV and MAYV.

Pollution Exposure During Teen Years May Disrupt Menstrual Cycle

January 31, 2018

The researchers found that for every 45 μg/m3 increase in average high school TSP, there was an increased odds for moderate irregularity, persistent irregularity.