Inverse Link for Mediterranean Diet Score, Severe Psoriasis

Significant inverse correlation between MEDI-LITE score and having severe psoriasis.
Significant inverse correlation between MEDI-LITE score and having severe psoriasis.

HealthDay News — Patients with severe psoriasis have low levels of adherence to the Mediterranean diet (MEDI-LITE), according to a study published online July 25 in JAMA Dermatology.

Céline Phan, MD, from Mondor Hospital in France, and colleagues examined the correlation between a score reflecting adhesion to MEDI-LITE and the onset and/or severity of psoriasis in the NutriNet-Santé program. Patients with psoriasis were identified via validated online self-completed questionnaire and were classified according to disease severity. During the first 2 years of participation in the cohort, data on dietary intake were gathered to calculate the MEDI-LITE score. 

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The researchers found that 23% of the 158,361 NutriNet Santé participants responded to the psoriasis questionnaire. Overall, 3557 individuals (10%) reported having psoriasis. In 24.7% of cases, the condition was severe, and incident cases were recorded in 8.4%. There was a significant inverse correlation between MEDI-LITE score and having severe psoriasis (odds ratio, 0.71 for the MEDI-LITE score's second tertile [95% confidence interval, 0.55 to 0.92] and odds ratio, 0.78 for the third tertile [95% confidence interval, 0.59 to 1.01]) after adjustment for confounding variables.

"If these findings are confirmed, adherence to a Mediterranean diet should be integrated into the routine management of moderate to severe psoriasis," the authors write.

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