Cancer Rates Assessed Post-Endometrial Ablation
HealthDay News — For women in Finland, endometrial ablation is not associated with increased risk of endometrial or breast cancer, according to a study published in the September issue of Obstetrics & Gynecology.
Tuuli Soini, MD, from the Hyvinkää Hospital in Finland, and colleagues conducted a retrospective study involving women with endometrial ablation at ages 30 to 49 years in Finland. The authors examined cancer incidences in the endometrial ablation cohort compared with those in the background population of the same age.
During the follow-up of 39,892 women-years, the researchers identified 154 cancers (standardized incidence ratio, 0.96; 95% confidence interval, 0.82 to 1.13) among 5,484 women treated with endometrial ablation. For endometrial cancer and breast cancer, the standardized incidence ratios were 0.56 (95% confidence interval, 0.12 to 1.64) and 0.86 (95% confidence interval, 0.67 to 1.09), respectively. Overall, 19.8% of women had post-ablation hysterectomy. Compared with 26,938 women in a control group, the risk of hysterectomy was almost four-fold in the endometrial ablation cohort (adjusted hazard ratio, 3.63; 95% confidence interval, 3.32 to 3.96). Leiomyomas, age younger than 35 years, at least 2 prior cesarean deliveries, and history of sterilization were factors that predisposed patients to post-ablation hysterectomy.
"Endometrial ablation was not associated with an elevated endometrial cancer or breast cancer risk in Finland," the authors write.