Guidelines have been developed for use of opioids for uncomplicated spontaneous vaginal birth; the draft consensus guidelines were published online.
In addition to the new authorized generic, Evzio is now available at $178 per carton (2 auto-injectors per carton) for government agencies, first responders, health departments, and other qualifying groups when they purchase directly from kaléo or authorized distributors.
reSET-O is intended for use as an adjunct to outpatient treatment that includes transmucosal buprenorphine (medication-assisted-treatment [MAT]) and contingency management for patients aged ≥18 years who are currently under clinician supervision.
Chronic opioid use during pregnancy that causes neonatal abstinence syndrome is associated with smaller neonatal head circumference, according to a new study.
An ultrarestrictive opioid prescription protocol (UROPP) can reduce the number of opioids prescribed to patients after gynecologic and abdominal surgery without negative health consequences, according to a new study.
An investigational transdermal cannabidiol gel was well-tolerated and consistently effective for adults with focal epilepsy.
The Agency conducted testing on 26 separate kratom products which revealed levels of nickel and lead considered not safe for human consumption.
A study by the National Survey of Drug Use and Health (NSDUH) found that from 2002-2014 the proportion of adults aged 50 to 64 who reported cannabis use in the past year more than tripled from 2.9% to 9.0%. Among adults age 65 or older, there was more than a ten-fold increase (from 0.2% to 2.1%).
While approved in Europe, Asia and Latin America, tianeptine is an unscheduled pharmaceutical agent in the US that has been linked to serious adverse events, including death, when used for recreational purposes.
Compared with being attracted only to the opposite sex, being attracted mostly to the opposite sex or being equally attracted to both sexes correlated with higher odds for past-year opioid misuse (adjusted odds ratios, 2.15 and 1.78, respectively).
The vote was taken in a joint meeting of the Anesthetic and Analgesic Drug Products Advisory Committee and Drug Safety and Risk Management Advisory Committee.
Reports of pump failure, dosing errors, as well as other possible safety issues have prompted the Agency to issue the alert to make prescribers aware of the dangers associated with using medications not approved for intrathecal use.
The sublingual formulation of sufentanil offers a new treatment option for patients with nothing by mouth (NPO) status and patients with difficult IV access.
The patient's past medical history was significant for chronic kidney disease (stage 5) on nightly peritoneal dialysis, type 2 diabetes mellitus, peripheral neuropathy, gastroesophageal reflux disease, hypertension, and chronic pain.
Patients with SLE who experienced high pain levels and had a visit to the emergency department the previous year were more likely to use opioids.
There is $60 million earmarked for infants who are born drug-dependent and authorization for programs that place drug offenders into treatment instead of in prison.
The training has information on how to use several products including a nasal atomizer, Narcan Nasal Spray and Evzio.
The researchers found that 83% of the patients required no narcotic medication postoperatively. Preoperative opioid use significantly predicted postoperative narcotic requirement.
There was a correlation between a positive result and older age, homelessness, heroin use, injection drug use, ever witnessing an overdose, and concern about overdose or drugs being laced with fentanyl.
The FDA is not bound by the Committee's recommendation but takes it into consideration when making its decision.
Oliceridine, a G-protein biased mu-opioid receptor (MOR) ligand, has a unique mechanism of action that allows for more selective pathway activation while avoiding a pathway associated with opioid-related adverse events.
Parents use unregulated cannabinoids to manage neurological disorders in children, including seizures, spasticity, and irritability in children with epilepsy, autism-spectrum disorder, and cerebral palsy.
An investigational treatment - CAM2038 (Braeburn) - currently under review for the treatment of moderate-to-severe opioid use disorder, has demonstrated a reduction in Chronic Low Back Pain (CLBP) compared to placebo in patients previously on long-term daily opioid therapy.
As part of the REMS program, drug companies with approved opioid analgesics must make training available to prescribers and provide unrestricted grants to accredited continuing education providers for the development of education courses.
The prevalences of both chronic pain and high-impact chronic pain were higher among women; older adults; adults who were previously, but not currently, employed; adults living in poverty; those with public health insurance; and rural residents.