Musculoskeletal Pain

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

By July 18, 2018

The 16-week, double-blind, placebo-controlled, multicenter, parallel-group study included 698 patients who were randomized to 3 treatment groups: 2 doses of tanezumab 2.5mg; 1 dose of tanezumab 2.5mg followed by tanezumab 5mg, or 2 doses of placebo; each injection was administered once every 8 weeks.

Are Anticonvulsants Effective for Low Back Pain?

By July 03, 2018

For this review, the authors searched 5 large databases for studies that compared the use of anticonvulsants (i.e., topiramate, gabapentin, pregabalin) in adult patients with LBP, sciatica, or neurogenic claudication with placebo.

Coverage Policies Compared for Back Pain Medications

June 25, 2018

Utilization management common for opioids; often relies on 30-day limits rather than prior authorization

Metformin Use Linked to Reduced Risk of Statin-Associated Muscle Pain

By March 27, 2018

Statin-associated muscle pain can hinder medication adherence which could potentially lead to an increased risk of cardiovascular events.

Many Patients Receive Inappropriate Tests, Treatments for Low Back Pain

By March 22, 2018

More emphasis should be placed on self-management, physical and psychological therapies for treating low back pain, rather than pharmacological or surgical treatments.

Is Cranial Electrical Stimulation Effective for Pain, Depression, Anxiety?

February 13, 2018

In patients with anxiety and depression, low-strength evidence of a possible modest benefit was seen in 4 trials conducted more than 40 years ago and in one recent trial compared with sham treatments.

ASHP: Revised Standards can Build Framework for Opioid Stewardship

December 06, 2017

The new and revised standards from The Joint Commission were published in July 2017 to address some of the issues associated with over-prescribing and lack of monitoring.

New Drug-Free Therapy Available for Arthritis Pain

By November 16, 2017

The device has 14 pre-set therapy modes designed to block acute or chronic pain or to imitate exercise recovery, endurance and muscle strength.

DEA Sets Date to Collection Unwanted Rx Drugs From Public

October 25, 2017

Last April, 450 tons of prescription drugs were collected at almost 5,500 sites operated by the DEA and more than 4,200 state and local law enforcement partners.

Neuropathic Pain in Rheumatoid Arthritis Linked to Vitamin D Deficiency

September 13, 2017

Among patients with serum vitamin D levels <20 ng/mL, the prevalence of NP was 5.8 times higher than in patients with vitamin D levels ≥30 ng/mL.

Are OTC Lidocaine Patches as Effective as Rx for Localized Pain?

By August 15, 2017

Study authors sought to compare OTC lidocaine 3.6% with menthol 1.25% patches vs. Rx lidocaine 5% as well as to placebo.

'Smart' Undergarment Helps Reduce Stress on the Lower Back

By August 02, 2017

When wearing the clothing lower back activity was reduced by an average of 15 to 45%.

Impax Launches Generic Skelaxin

By July 21, 2017

Metaxalone, a muscle relaxant (central), is indicated as an adjunct to rest, physical therapy, and other remedies for relief of discomfort associated with acute, painful musculoskeletal conditions.

Is Radiofrequency Denervation Effective for Chronic Low Back Pain?

By July 05, 2017

Results showed a statistically significantly, but not a clinically important, improvement in two of the trials which evaluated radiofrequency denervation for the sacroiliac joints (−0.71 (95% CI, −1.35 to −0.06) and a combination of the facet joints, sacroiliac joints or intervertebral disks (−0.99 (95% CI, −1.73 to −0.25) at 3 months.

Treatments Compared for Managing Musculoskeletal Pain in Primary Care

By June 27, 2017

In general, the best available evidence pointed to self-management advice, exercise therapy and psychosocial interventions as effective strategies for managing musculoskeletal pain in primary care.

DRG Stimulation Helpful for Pain Due to Failed Back Surgery Syndrome

May 24, 2017

Pain relief for patients with discogenic low back pain due to failed back surgery syndrome

Law Enforcement Data Indicate a Rise in Gabapentin Misuse

By May 15, 2017

Using data from the Drug Diversion Program of the Researched Abuse, Diversion, and Addiction-Related Surveillance System, the authors were able to calculate the rates of gabapentin diversion (per 100,000 population) for each quarter from 2002-2015

Risk of Death Up with Long-Term Quinine Exposure

May 15, 2017

Increased risk of death more pronounced among those younger than 50 years regardless of indication

Movement Disorders Examined in Current, Past Stimulant Drug Users

By April 21, 2017

The researchers concluded that stimulant drug use may result in acute stimulant-induced tremor as well as long-term proprioceptive deficits in terms of arm-droop.

Massage Therapy Effective for Chronic Low Back Pain

April 17, 2017

Patients over 50 tend to respond best, researchers say

Short-Term PNS May Cut Low Back Pain, Analgesic Use

March 20, 2017

Novel short-term PNS produced pain relief, reduced medication use in two patients with chronic LBP

Obese Patients with Chronic Pain May Benefit from Anti-Inflammatory Diet

March 13, 2017

Data indicate that dietary intake can mediate relationship of body fat to body pain

Low Back Pain Treatment Guidelines Released

By February 14, 2017

The recommendations are intended for all clinicians treating adult patients with acute, suabcute, or chronic low back pain.

How Effective Are NSAIDs for Spinal Pain?

February 02, 2017

New research from The George Institute for Global Health concluded that common nonsteroidal anti-inflammatory drugs (NSAIDs) showed little benefit for spinal pain compared to placebo.

Ablation of Basivertebral Nerve May Improve Chronic Back Pain

January 24, 2017

Improvement in self-reported outcomes at three months in patients with chronic lumbar back pain

Spinal Cord Stimulation May Cut Opioid Use in Chronic Pain

By January 23, 2017

Spinal cord stimulation was found to help decrease or stabilize opioid use in patients with chronic pain.

Yoga for Chronic Low Back Pain: Is it Effective?

By January 12, 2017

Findings from a systematic review showed low- to moderate-certainty evidence that yoga vs. non-exercise controls resulted in small to moderate improvements in back-related function at Months 3 and 6.

Top 10 Most Costly Conditions in the U.S. Announced in New Report

By December 27, 2016

The highest amounts of spending were seen with these 10 conditions.

VR Gaming Shows Promise in Relieving Phantom Limb Pain in Amputees

December 05, 2016

Amputees who experience phantom limb pain may benefit from playing a virtual reality game that simulates the movement of missing limbs, according to a study published online in The Lancet.

Treatment for Painful Foot Nerve Disorder Gets Fast Track Designation

By November 15, 2016

Centrexion announced that the Food and Drug Administration (FDA) has granted Fast Track designation to CNTX-4975, a novel therapy intended to treat Morton's neuroma.